16 March 2022 : Animal Research
A New Target of the Four-Herb Chinese Medicine for Wound Repair Promoted by Mitochondrial Metabolism Using Protein Acetylation Analysis
Zhongzhi Zhou1ABCDEFG, Li Chen23ABCDEFG, Yuxin Su4ABCDEF, Meirong Li3CE, Lingzhi Zhong3BCD, Liangying Liao1DEF, Yarong Ding2CEF, Mulin Liu2CDE, Zhonghang Yuan2CDE, Wei Wang2CEF, Xinyu Hang2BC, Xiuna Fang2DE, Xiaobing Fu3AEG*, Wenjun He3ADEF, Qian Hou3ABFGDOI: 10.12659/MSM.934816
Med Sci Monit 2022; 28:e934816
Table 4 GO annotation for upregulated and downregulated acetylated proteins.
| GO terms level 1 | GO terms level 2 | No. of upregulated acetylated proteins | No. of downregulated acetylated proteins |
|---|---|---|---|
| Cellular process | 78 | 28 | |
| Single-organism process | 71 | 24 | |
| Metabolic process | 56 | 17 | |
| Biological regulation | 54 | 21 | |
| Multicellular organismal process | 49 | 21 | |
| Response to stimulus | 44 | 20 | |
| Developmental process | 39 | 15 | |
| Organelle | 86 | 27 | |
| Cell | 85 | 30 | |
| Extracellular region | 63 | 24 | |
| Macromolecular complex | 51 | 18 | |
| Membrane | 50 | 13 | |
| Binding | 75 | 31 | |
| Catalytic activity | 43 | 12 | |
| Structural molecule activity | 15 | 3 | |
| Transporter activity | 7 | 3 |