16 March 2022 : Clinical Research
Effect of Cerebral Microbleeds on Cognitive Function and Quality of Life in Parkinson Disease
Qixiong Qin1ABCDEF, Hengming Wan2C, Danlei Wang1B, Jingyi Li1B, Qingmei Yang1B, Jingwei Zhao1B, Zheng Xue1ADFG*DOI: 10.12659/MSM.935026
Med Sci Monit 2022; 28:e935026
Table 3 Quality of life assessment in patients with different locations of cerebral microbleeds.
| CMBs free (n=162) | Lobar CMBs (n=15) | Deep CMBs (n=17) | Mixed CMBs (n=10) | p-value | |
|---|---|---|---|---|---|
| PDQ-39 SI | 24.83±13.55 | 30.94±15.46 | 28.51±14.14 | 39.36±12.40# | 0.012 |
| Mobility SI | 29.52±23.55 | 44.33±29 | 34.56±26.53 | 47.75±23.44 | 0.035 |
| Activity of daily living SI | 28.02±20.39 | 38.89±29.99 | 30.39±23.23 | 50.41±21.73# | 0.023 |
| Emotional well-beings SI | 27.48±18.26 | 31.67±17.27 | 28.68±19.40 | 26.25±17.63 | 0.860 |
| Stigma SI | 24.32±23.14 | 25.00±31.16 | 25.74±26.13 | 37.38±16.80 | 0.228 |
| Social support SI | 8.17±17.13 | 7.78±14.92 | 8.82±16.53 | 10.83±20.05 | 0.984 |
| Cognitions SI | 27.88±19.81 | 29.17±19.42 | 35.05±20.52 | 41.70±19.43 | 0.037 |
| Communication SI | 16.08±20.18 | 24.99±24.19 | 17.16±26.76 | 26.67±21.44 | 0.189 |
| Bodily discomfort SI | 19.23±20.18 | 15.55±15.06 | 25.98±16.89 | 20.00±18.09 | 0.248 |
| Data are presented as means±standard deviation. The comparison among groups was performed using Kruskal-Wallis test, and Bonferroni corrections were used for multiple comparisons. # Compared with CMB-free group, the difference was statistically significant. CMBs – cerebral microbleeds; PDQ – 39-item Parkinson’s disease questionnaire; SI – summary index. | |||||