Downregulated Expression of RIPOR3 Correlated with Immune Infiltrates Predicts Poor Prognosis in Oral Tongue Cancer

12 March 2022: Lab/In Vitro Research

Kai Zhang ^1BCDE , Junlong Da ^1F , Xiaoyao Liu ^1F , Xinpeng Liu ^1F , Jianqun Wang ^1F , Han Jin ^1D , Ying Li ^1D , Bin Zhang ^12AG*

DOI: 10.12659/MSM.935055

Med Sci Monit 2022; 28:e935055

Table 1 Univariate and multivariate Cox logistic regression analysis of RIPOR3 expression and other clinical pathological factors.

Parameters	Univariate analysis			Multivariate analysis
Parameters	HR	95% CI	P value	HR	95% CI	P value
Age	1.007	0.977–1.038	0.625
Sex	0.645	0.307–1.355	0.247
Stage	1.470	0.974–2.219	0.067
Grade	1.902	0.998–3.626	0.050	2.941	1.359–6.366	0.006
T	1.804	1.197–2.719	0.005	2.352	1.271–4.351	0.006
N	1.390	0.925–2.088	0.113	1.957	1.027–3.727	0.041
Surgery	0.212	0.080–0.566	0.002	0.113	0.030–0.431	0.001
Radiation	0.442	0.207–0.944	0.035	0.206	0.084–0.504
RIPOR3	0.256	0.109–0.643	0.003	0.276	0.107–0.708	0.007
HR – hazard ratio; CI – confidence interval; T – tumor; N – lymph node.