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28 December 2021 : Review article  

A Review of the Impact of Neutrophils and Neutrophil Extracellular Traps (NETs) on the Development of Aortic Aneurysms in Animal and Human Studies

Milena Michalska ORCID logo1ABCDEFG*, Tadeusz Grochowiecki1AEFG, Tomasz Jakimowicz ORCID logo1DEF, Sławomir Nazarewski1D

DOI: 10.12659/MSM.935134

Med Sci Monit 2021; 27:e935134

Table 1 Comparison of animal models of aortic aneurysm.

ModelAdvantagesLimitationsSeverityMechanismRuptureDissectionPositive risk factors of AAA in humans
Angiotensin II perfusion [,]10 ModerateYesYes
Elastase perfusion [,]10 ModerateNoNo
Calcium chloride or phosphate usage [,]10 MildNoNo
Xenograft []5 SevereYesYes

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750