Retrospective Study from a Single Center to Evaluate the Association Between Sex and Serum Uric Acid Levels in 950 Patients with Atrial Fibrillation

12 May 2022: Clinical Research

Xia Zhong ^1ABCE , Huachen Jiao ^2BDFG* , Dongsheng Zhao ^1BCD , Jing Teng ^1ADF

DOI: 10.12659/MSM.935273

Med Sci Monit 2022; 28:e935273

Table 4 Association between levels of serum uric acid and metabolic factors in patients with paroxysmal atrial fibrillation by sex.

Variable	Male patients (n=180)				Female patients (n=152)
Variable	<5.5 mg/dL	5.5–6.5 mg/dL	>6.5 mg/dL	P value	<4.2 mg/dL	4.2–5.0 mg/dL	>5.0 mg/dL	P value
Number, n	80	46	54		45	40	67
Creatinine, μmoI/L	71.15±17.60	82.59±18.87	88.28±31.34	0.005^*	54.36±13.43	68.50±46.35	86.88±38.16	^*
AST, U/L	25.46±24.23	28.11±27.00	29.28±37.87	0.243	20.76±9.39	20.50±7.58	23.19±14.47	0.402
ALT, U/L	27.75±30.42	25.30±28.85	27.57±24.08	0.885	17.38±9.63	18.85±11.89	20.19±15.92	0.547
APOA1, g/L	1.05±0.31	1.07±0.20	1.03±0.24	0.754	1.18±0.27	1.19±0.25	1.18±0.30	0.981
APOB, g/L	0.84±1.02	0.79±0.21	0.83±0.26	0.927	0.76±0.20	0.84±0.27	0.87±0.30	0.100
ALB, mg/L	35.72±5.40	38.53±4.62	38.43±4.58	0.001^*	37.20±5.57	37.77±4.48	38.16±4.31	0.579
PAB, mg/L	172.15±68.57	209.17±66.29	207.91±60.42	0.001^*	172.82±68.04	193.65±53.31	195.67±59.44	0.124
TG, mmol/L	0.99±0.43	1.26±0.85	1.14±0.52	0.043^*	1.14±0.58	1.64±2.51	1.30±0.71	0.251
TC, mmol/L	3.78±0.93	4.16±0.89	4.14±1.16	0.049^*	4.20±1.07	4.63±1.39	4.54±1.29	0.235
LDL-C, mmol/L	2.16±0.69	2.49±0.72	2.64±0.92	0.001^*	2.51±0.88	2.67±1.09	2.76±1.26	0.509
HDL-C, mmol/L	1.06±0.40	1.01±0.21	0.96±0.22	0.190	1.13±0.34	1.18±0.33	1.14±0.40	0.800
Data are presented as mean±SD. AST – aspartate aminotransferase; ALT – alanine aminotransferase; APOA1 – apolipoprotein A1; APOB – apolipoprotein B; ALB – albumin; PAB – prealbumin; TG – triglyceride; TC – total cholesterol; LDL-C – low-density lipoprotein cholesterol; HDL-C – high-density lipoprotein cholesterol. ^* Statistically significant value (