External Quality Assessment of Maternal Serum Levels of Alpha-Fetoprotein, Free Beta-Human Chorionic Gonadotropin, and Unconjugated Estriol in Detecting Down Syndrome and Neural Tube Defects in the Second Trimester of 87 Maternal Serum Samples, Based on 105-139 Days

13 April 2022 : Clinical Research

Yiming Chen

^12AEG*, Yijie Chen

^2BE, Yezhen Shi^3CD, Wenwen Ning^2BE, Xiaoying Wang^1B, Liyao Li^1BC, Huimin Zhang^2F

DOI: 10.12659/MSM.935573

Med Sci Monit 2022; 28:e935573

Background Material and Methods Results Discussion Conclusions References

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Supplementary Table 3 Correlation analysis of unconjugated estriol (uE3) multiple of median (MoM) value in 6 laboratories.

Laboratory		Lab A	Lab B	Lab C	Lab D	Lab E	Lab F
Lab A		1	0.973^**	0.966^**	0.967^**	0.978^**	0.913^**

	N	87	87	87	87	87	87
Lab B		0.973^**	1	0.977^**	0.986^**	0.985^**	0.934^**

	N	87	87	87	87	87	87
Lab C		0.966^**	0.977^**	1	0.959^**	0.976^**	0.917^**

	N	87	87	87	87	87	87
Lab D		0.967^**	0.986^**	0.959^**	1	0.968^**	0.926^**

	N	87	87	87	87	87	87
Lab E		0.978^**	0.985^**	0.976^**	0.968^**	1	0.918^**

	N	87	87	87	87	87	87
Lab F		0.913^**	0.934^**	0.917^**	0.926^**	0.918^**	1

	N	87	87	87	87	87	87
^** Correlation is significant at a 0.01 level (2-tailed).

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