13 April 2022 : Clinical Research
External Quality Assessment of Maternal Serum Levels of Alpha-Fetoprotein, Free Beta-Human Chorionic Gonadotropin, and Unconjugated Estriol in Detecting Down Syndrome and Neural Tube Defects in the Second Trimester of 87 Maternal Serum Samples, Based on 105-139 Days
Yiming Chen
12AEG*, Yijie Chen 2BE, Yezhen Shi3CD, Wenwen Ning2BE, Xiaoying Wang1B, Liyao Li1BC, Huimin Zhang2F
DOI: 10.12659/MSM.935573
Med Sci Monit 2022; 28:e935573
Table 3 Comparison of positive rate and detection rate of trisomy 21 in 6 different laboratories.
| Laboratory | N | T21 risk value distribution | T21 detection situation | ||||
|---|---|---|---|---|---|---|---|
| Low risk | High risk | PR (%) | Low risk | High risk | DR (%) | ||
| Lab A | 82 | 76 | 6 | 7.32 | 1 | 3 | 75.00 |
| Lab B | 82 | 78 | 4 | 4.88 | 1 | 3 | 75.00 |
| Lab C | 82 | 78 | 4 | 4.88 | 1 | 3 | 75.00 |
| Lab D | 82 | 78 | 4 | 4.88 | 1 | 3 | 75.00 |
| Lab E | 82 | 78 | 4 | 4.88 | 1 | 3 | 75.00 |
| Lab F | 82 | 75 | 7 | 8.54 | 1 | 3 | 75.00 |
| Lab – laboratory; T21 – trisomy 21; PR – positive rate; DR – detection rate. | |||||||