13 April 2022>: Clinical Research
External Quality Assessment of Maternal Serum Levels of Alpha-Fetoprotein, Free Beta-Human Chorionic Gonadotropin, and Unconjugated Estriol in Detecting Down Syndrome and Neural Tube Defects in the Second Trimester of 87 Maternal Serum Samples, Based on 105-139 Days
Yiming Chen 12AEG** , Yijie Chen 2BE* , Yezhen Shi 3CD , Wenwen Ning 2BE , Xiaoying Wang 1B , Liyao Li 1BC , Huimin Zhang 2FDOI: 10.12659/MSM.935573
Med Sci Monit 2022; 28:e935573
Table 3 Comparison of positive rate and detection rate of trisomy 21 in 6 different laboratories.
Laboratory | N | T21 risk value distribution | T21 detection situation | ||||
---|---|---|---|---|---|---|---|
Low risk | High risk | PR (%) | Low risk | High risk | DR (%) | ||
Lab A | 82 | 76 | 6 | 7.32 | 1 | 3 | 75.00 |
Lab B | 82 | 78 | 4 | 4.88 | 1 | 3 | 75.00 |
Lab C | 82 | 78 | 4 | 4.88 | 1 | 3 | 75.00 |
Lab D | 82 | 78 | 4 | 4.88 | 1 | 3 | 75.00 |
Lab E | 82 | 78 | 4 | 4.88 | 1 | 3 | 75.00 |
Lab F | 82 | 75 | 7 | 8.54 | 1 | 3 | 75.00 |
Lab – laboratory; T21 – trisomy 21; PR – positive rate; DR – detection rate. |