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20 March 2022: Clinical Research

Aldosterone-to-Renin Ratio Is Associated with Diabetic Nephropathy in Type 2 Diabetic Patients: A Single-Center Retrospective Study

Mariko Higa 1ABCDEF* , Takamasa Ichijo 1AC , Takahisa Hirose 2E

DOI: 10.12659/MSM.935615

Med Sci Monit 2022; 28:e935615

Table 1 Clinical characteristics of the patients studied.

SEX (Male/Female)51/19
Age (years)53.3±11.0
BMI (kg/m)25.5±4.0
Diabetic duration (years)7.1±6.1
Diabetic treatment: Insulin/OHA/Diet alone36/29/5
HbA1c (%)9.9±1.9
Systolic BP (mmHg)115.3±24.1
Diastolic BP (mmHg)75.0±12.2
Hypertension (%)30
Use of CCB (%)8.6
LDL-cholesterol (mg/dl)118.2±37.1
Triglyceride (mg/dl)219.8±352.0
Serum creatinine (mg/dl)0.68±0.18
eGFR (ml/min/1.73 m)86.9±21.8
Albuminuria (mg/day)22.7±22.5
PRA (ng/ml/hr)1.83±1.06
Plasma aldpsterone (ng/dl)11.18±3.43
OHA – oral hypoglycemic agents; BP – blood pressure; CCB – calcium channel blocker; eGFR – estimated glomerular filtration rate; PRA – plasma renin activity; ARR – aldosterone/renin ratio. Values are mean±SD.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750