03 June 2022: Clinical Research
Early Enteral Nutrition Can Reduce Incidence of Postoperative Hydrocephalus in Patients with Severe Hypertensive Intracerebral Hemorrhage
Zhi Cai BCE , Kai Zhao AEG , Yu Li BC , Xueyan Wan B , Chunlin Li B , Hongquan Niu DF , Kai Shu DF , Ting Lei A*DOI: 10.12659/MSM.935850
Med Sci Monit 2022; 28:e935850
Table 1 The clinical characteristics of 146 patients with severe HICH.
| Variables | Values |
|---|---|
| Age, years (SD) | 51.7 (11.4) |
| Gender (%) | |
| Male | 87 (59.6) |
| Female | 59 (40.4) |
| Nutritional status at admission | |
| BMI, kg/m (SD) | 24.1 (3.5) |
| Mid-arm muscle circumference, cm (SD) | 30.1 (4.5) |
| Albumin, g/L (M (P, P)) | 42.4 (39.3, 47.4) |
| SGA (%) | |
| Well-nourished | 9 (6.2) |
| Moderately malnourished | 99 (67.8) |
| Severely malnourished | 38 (26.0) |
| Hematoma location (%) | |
| Lobes | 36 (24.6) |
| Basal ganglia | 81 (55.5) |
| Thalamus | 15 (10.3) |
| Cerebellum | 14 (9.6) |
| Volume of hematoma, ml (SD) | 49.5 (23.6) |
| SAH (%) | 25 (17.1) |
| IVH (%) | 84 (57.5) |
| Preoperative GCS (M (P2, P)) | 6.2 (5,8) |
| Surgical treatment (%) | |
| Hematoma removal | 103 (70.5) |
| DC | 28 (15.0) |
| EVD | 45 (34.9) |
| EN application (%) | |
| Early EN | 51 (34.9) |
| Delayed EN | 95 (65.1) |
| Supported PN administration (%) | 87 (59.6) |
| Hydrocephalus (%) | |
| Acute | 27 (18.5) |
| Chronic | 20 (13.7) |
| Postoperative GCS (M (P, P)) | 10.4 (7,14) |
| mRS (SD) | 4.2 (0.4) |
| Nutritional status at two weeks postoperatively | |
| BMI, kg/m (SD) | 23.0 (3.0) |
| Mid-arm muscle circumference, cm (SD) | 28.6 (3.9) |
| Albumin, g/L (SD) | 33.6 (4.9) |
| SGA (%) | |
| Well-nourished | 17 (11.6) |
| Moderately malnourished | 101 (69.2) |
| Severely malnourished | 28 (19.2) |
| Laboratory results | |
| White blood cells, 10 (M (P, P)) | 14.3 (10.5, 17.5) |
| Neutrophil, 10 (M (P, P)) | 12.0 (8.4, 15.0) |
| Lymphocyte, 10 (M (P, P)) | 1.2 (0.9, 1.4) |
| Monocyte, 10 (M (P, P)) | 1.2 (0.8, 1.5) |
| Platelet, 10 (M (P, P)) | 265.4 (174.3, 344.3) |
| NLR (M (P, P)) | 11.2 (7.1, 13.8) |
| dNLR (M (P, P)) | 2.0 (1.7, 2.2) |
| MLR (M (P, P)) | 1.0 (0.7, 1.2) |
| PLR (M (P, P)) | 236.8 (166.4, 280.3) |
| CRP, mg/L (M (P, P)) | 41.6 (10.7, 61.7) |
| LDH, U/L (M (P, P)) | 286.1 (213.8, 360.0) |
| BMI – body mass index; CRP – C-reactive protein; DC – decompression craniectomy; dNLR – derived NLR; EN – enteral nutrition; EVD – extraventricular drainage; GCS – Glasgow coma scale; IVH – intraventricular hemorrhage; LDH – lactate dehydrogenase; MLR – monocyte-to-lymphocyte ratio; mRS – Modified Rankin Scale; NLR – neutrophil-to-lymphocyte ratio; PLR – platelet-to-lymphocyte ratio; PN – parenteral nutrition; SAH – subarachnoid hemorrhage; SD – standard deviation; SGA – subjective global assessment. | |