03 June 2022 : Clinical Research
Early Enteral Nutrition Can Reduce Incidence of Postoperative Hydrocephalus in Patients with Severe Hypertensive Intracerebral Hemorrhage
Zhi Cai1BCE, Kai Zhao1AEG, Yu Li1BC, Xueyan Wan1B, Chunlin Li1B, Hongquan Niu1DF, Kai Shu1DF, Ting Lei1A*DOI: 10.12659/MSM.935850
Med Sci Monit 2022; 28:e935850
Table 4 The relationship between EN application and postoperative laboratory examinations of systematic inflammation reaction.
| Variables | Early-EN | Delayed-EN | P value |
|---|---|---|---|
| Acute hydrocephalus (%) | 6 (11.8) | 21 (22.1) | 0.125 |
| Chronic hydrocephalus (%) | 3 (5.9) | 17 (17.9) | * |
| White blood cells, 10 (M (P, P)) | 12.9 (9.2, 16.6) | 15.1 (11.2, 19.0) | * |
| Neutrophil, 10 (M (P, P)) | 10.7 (7.0, 14.0) | 12.7 (9.1, 15.2) | * |
| Lymphocyte, 10 (M (P, P)) | 1.2 (0.8, 1.4) | 1.2 (0.9, 1.5) | 0.895 |
| Monocyte, 10 (M (P, P)) | 1.1 (0.8, 1.5) | 1.2 (0.8, 1.5) | 0.385 |
| Platelet, 10 (M (P, P)) | 258.5 (157, 348) | 269.1 (184, 343) | 0.504 |
| NLR, (M (P, P)) | 9.62 (6.5, 11.9) | 12.1 (7.7, 15.1) | * |
| dNLR, (M (P, P)) | 2.0 (1.8, 2.2) | 2.0 (1.8, 2.2) | 0.607 |
| MLR, (M (P, P)) | 1.0 (0.8, 1.2) | 1.0 (0.8, 1.2) | 0.607 |
| PLR, (M (P, P)) | 229.9 (165.5, 276.2) | 240.6 (166.7, 283.5) | 0.566 |
| CRP, (M (P, P)) | 35.2 (10.1, 6.4) | 45.1 (12.5, 65.1) | 0.244 |
| LDH, U/L (M (P, P)) | 260.9 (185, 302) | 299.6 (238, 361) | * |
| IL-1β, pg/ml (M (P, P)) (n=50) | 5.7 (2.5, 7.5) | 7.9 (4.5, 11.0) | * |
| IL-6, pg/ml (M (P, P)) (n=50) | 70.3 (36.5, 101.1) | 88.2 (40.6, 129.7) | 0.599 |
| TNF-α, pg/ml (SD) (n=50) | 8.3 (2.3) | 10.5 (3.8) | * |
| CRP – C-reactive protein; dNLR – derived NLR; EN – enteral nutrition; IL – interleukin; LDH – lactate dehydrogenase; MLR – monocyte-to-lymphocyte ratio; NLR – neutrophil-to-lymphocyte ratio; PLR – platelet-to-lymphocyte ratio; SD – standard deviation; TNF – Tumor Necrosis Factor. * | |||