23 March 2022 : Clinical Research
Intravenous Lidocaine for Postoperative Analgesia in 90 patients After Total Knee Arthroplasty and Limb Fractures
Rajmonda Nallbani
1ABCDEFG*, Edmond Komoni2ABCDEF, Fatos Sada1ABCDEF, Ismet Q. Jusufi3ABCDEF, Antigona Hasani 1ABCDEF
DOI: 10.12659/MSM.935852
Med Sci Monit 2022; 28:e935852
Table 2 Comparison of mean VAS at rest and during movement in patients treated with lidocaine and controls.
| VAS at rest | Lidocaine | Control | P-value | VAS during movement | Lidocaine | Control | P-value |
|---|---|---|---|---|---|---|---|
| n | 40 | 41 | 40 | 41 | |||
| 0 min | 4.5±1.3 | 5.0±1.3 | P=0.125 | 0 min | 4.6±0.7 | 5.1±0.7 | P=0.01 |
| 15 min | 4.7±1.6 | 5.1±1.2 | P=0.203 | 15 min | 4.5±0.8 | 5.2±1.0 | P=0.003 |
| 30 min | 4.0±0.7 | 4.6±1.0 | P=0.003 | 30 min | 4.7±0.8 | 5.5±0.9 | P<0.001 |
| 1 h | 2.5±0.7 | 5.1±0.6 | P<0.001 | 1 h | 4.5±0.5 | 5.8±0.7 | P<0.001 |
| 6 h | 2.8±0.5 | 6.8±0.4 | P<0.001 | 6 h | 3.6±0.7 | 7.9±0.8 | P<0.001 |
| 12 h | 2.4±0.5 | 5.5±0.7 | P<0.001 | 12 h | 3.1±0.5 | 7.0±1.0 | P<0.001 |
| 24 h | 2.5±0.5 | 4.0±0.4 | P<0.001 | 24 h | 2.6±0.5 | 5.5±1.0 | P<0.001 |
| Data are expressed as mean±standard deviation or number (%). VAS – visual analog scale. | |||||||