05 May 2022 : Clinical Research
Predictive Value of Procalcitonin and Neutrophil-to-Lymphocyte Ratio Variations for Bloodstream Infection with Septic Shock
Peipei Liang1ABCDEFG, Feng Yu1AFG*DOI: 10.12659/MSM.935966
Med Sci Monit 2022; 28:e935966
Table 4 Performance of variables in predicting septic shock in patients with bloodstream infection.
| Test variables | AUC (95%CI) | P value | Specificity (%) | Sensitivity (%) |
|---|---|---|---|---|
| PCT0h | 0.743 (0.661, 0.826) | <0.001 | 78.00 | 70.50 |
| NLR0h | 0.756 (0.686, 0.825) | <0.001 | 92.13 | 38.36 |
| PCT48h | 0.769 (0.702, 0.836) | <0.001 | 94.08 | 32.23 |
| NLR48h | 0.682 (0.606, 0.758) | <0.001 | 81.25 | 41.09 |
| ΔPCT | 0.834 (0.778, 0.891) | <0.001 | 75.03 | 80.98 |
| ΔNLR | 0.852 (0.797, 0.908) | <0.001 | 76.98 | 83.82 |
| ΔPCT+ΔNLR | 0.937 (0.905, 0.970) | <0.001 | 92.80 | 80.02 |
| AUC – area under curve; NLR – neutrophil-to-lymphocyte ratio; PCT – procalcitonin; NLR0h – NLR at 0 hours; NLR48h – NLR at 48 hours; PCT0h – PCT at 0 hours; PCT48h – PCT at 48 hours. | ||||