25 June 2022 : Clinical Research
Serum TP53 Protein Level as a Sensitive Biomarker for the Diagnosis of Myocardial Damage in Children
Xianglin Zeng1EF, Chunwang Lin1AEG*, Yanna Sun1BD, Jianping Zhang1CFDOI: 10.12659/MSM.936248
Med Sci Monit 2022; 28:e936248
Table 2 Comparison of TP53, NT-proBNP, cTnI, and CK-MB levels in patients with secondary myocardial damage, patients without myocardial damage, and healthy children.
| Subjects | n | TP53 (ng/L) | NT-proBNP (ng/L,M) | cTnI (μg/L) | CK-MB (IU/L) |
|---|---|---|---|---|---|
| Myocardia damage | 50 | 10.20±1.20 | 505.3 | 0.23±0.13 | 28.30±5.13 |
| Non-myocardia damage | 50 | 0.30±0.10 | 107.8 | 0.02±0.01 | 12.24±4.29 |
| Healthy children | 0.21±0.10 | 59.7 | 0.01±0.01 | 6.31±3.11 | |
| χ | 63.25 | 40.35 | 45.21 | 35.27 | |
| 0.000 | 0.000 | 0.000 | 0.000 |