24 April 2022: Clinical Research
Prophylactic Use of Antibiotics for Fever After Drainage Removal Following a Dural Tear During Lumbar Spinal Surgery: A Retrospective Study
Yuhuai Liu 1ABCDEF* , Qinghua Tan 1ABCEF* , Jie Qin 1ACD , Yan Cai 1B , Ning Ning 2C , Rui Zhang 3B , Bo Dong 4B , Xijing He 1DEG , Dong Wang 1CD , Bo Zhao 1ACDEG*DOI: 10.12659/MSM.936652
Med Sci Monit 2022; 28:e936652
Table 5 Characteristics of fever after drainage removal (FDR) patients receiving various treatments.
| Parameters | No antibiotics | Ceftriaxone | Vancomycin | Ceftriaxone plus Vancomycin | Other antibiotics | P |
|---|---|---|---|---|---|---|
| Sex (M/F) | 9/12 | 20/22 | 11/14 | 14/18 | 35/43 | 0.9962 |
| Age (Yrs, Mean±Sd) | 66.4±10.2 | 70.5±9.6 | 68.3±11.3 | 70.1±8.4 | 72.5±11.2 | 0.123 |
| Age groups (Yrs) | ||||||
| 2 | 2 | 3 | 4 | 2 | 0.545 | |
| 60–70 | 10 | 21 | 12 | 16 | 35 | |
| >70 | 9 | 19 | 10 | 12 | 41 | |
| Body weight (Kg) | 75.5±10.8 | 71.7±9.6 | 68.4±12.7 | 72.6±11.9 | 69.7±11.3 | 0.163 |
| BMI groups (Kg/m) | ||||||
| 5 | 11 | 4 | 7 | 22 | 0.478 | |
| 25–30 | 9 | 21 | 13 | 20 | 30 | |
| >30 | 7 | 10 | 5 | 26 | ||
| Smoking | 8/21 | 14/42 | 9/25 | 10/32 | 27/78 | 0.988 |
| Other disease | ||||||
| Hypertension | 8 | 14 | 9 | 11 | 29 | 1.0 |
| Diabetes | 3 | 7 | 4 | 5 | 12 | |
| Osteoporosis | 2 | 5 | 3 | 4 | 9 | |
| Previous surgery | 9 | 25 | 13 | 23 | 48 | 0.27 |
| Diagnosis | ||||||
| Spinal stenosis | 3 | 7 | 4 | 4 | 14 | 1.0 |
| Degenerative disc disease | 6 | 8 | 5 | 5 | 18 | |
| Spondylolysis | 3 | 9 | 5 | 6 | 17 | |
| Deformity | 2 | 6 | 3 | 5 | 10 | |
| Primary intraspinal tumor | 5 | 10 | 7 | 10 | 15 | |
| Others | 2 | 2 | 1 | 2 | 4 |