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04 July 2022: Clinical Research

Post-Kidney Transplantation Results After Circulatory or Brain Death Without Pre-Mortem Heparin Administration

Jan Roman 12ABDEF , František Jalůvka 12ABE , Petr Ostruszka 1A , Petr Jelínek 12EF , Ján Hrubovčák 1B , Pavel Havránek 13BDF , Adéla Vrtková 45BCD , Zdeněk Lys 3BE , Jarmila Dědochová 3AB , Václav Procházka 26EG*

DOI: 10.12659/MSM.936877

Med Sci Monit 2022; 28:e936877

Table 3 Basic descriptive parameters of kidney recipients.

Median (IQR) or n (%)iP-valueiv
DBDii (n=79)DCDiii (n=20)
Age (years)55 (46–62)48 (42–63)0.467
Weight (kg)82 (74–93)82 (74–88)0.972
Body mass index (BMI)26.7 (24.4–30.0)26.5 (25.0–28.1)0.708
Body surface area (BSA)v 1.98 (1.86–2.15)1.99 (1.87–2.07)0.913
BSA donor/recipient ratio0.97 (0.85–1.08)0.95 (0.89–1.07)0.705
Duration of chronic hemodialysis (months)23 (13–29)21 (12–46)0.844
Compatibility index13 (12–16)14 (7–17)0.819
Preopreative PRA (%)vi 0 (0-0)0 (0-0)0.097
Maximal PRA (%)vi 0 (0–3)0 (0-0)0.213
Sex (Male)59 (75)14 (70)0.888
Arterial hypertension (Yes)75 (95)17 (85)0.289
Diabetes mellitus (Yes)18 (23)6 (30)0.704
Ischemic heart disease (Yes)22 (28)3 (15)0.372
COPDvii 8 (10)0 (0)0.327
Smoking (Yes)15 (19)4 (20)0.610
Number of prior kidney transplantations0.116
 058 (73)19 (95)
 120 (25)1 (5)
 21 (2)0 (0)
Chronic hemodialysis (Yes)76 (96)20 (100)0.877
Dialysis preoperatively (Yes)21 (27)6 (30)0.980
Chronic dialysis
 Chronic hemodialysis71 (90)12 (60)
 Chronic peritoneal dialysis4 (5)7 (35)
 Chronic combined dialysis1 (1)1 (5)
 No3 (4)0 (0)
Induction
 Anti-CD2521 (27)3 (15)
 ATGviii 14 (18)14 (70)
 Anti-CD25 + ATGviii 1 (1)0 (0)
 No43 (54)3 (15)
i The median with the interquartile range or the absolute frequency and relative frequency in percentages;
ii DBD – Donors after Brain Death;
iii DCD – Donors after Circulatory Death;
iv The p-value of the Mann-Whitney test or the Chi-square test of independence;
v BSA according to the Mosteller calculation method;
vi PRA – Panel-reactive antibodies;
vii COPD – Chronic Obstructive Pulmonary Disease;
viii ATG – anti-thymocyte globulin.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750