23 June 2022 : Clinical Research
Expression of the GZMB Gene Polymorphism, SNP rs8192917, in 990 Han Chinese Patients with Postoperative Keloids
Xiulin Wen12CDE, Huicong Du1BF, Xiaoyan Hao3BF, Jingrong Wang4BF, Yuan Guo1AG*DOI: 10.12659/MSM.936963
Med Sci Monit 2022; 28:e936963
Table 3 Results of haplotype-based association analyses.
| Locus | SNPs | Haplotype | F_A | F_U | χ2 | DF | P |
|---|---|---|---|---|---|---|---|
| rs2236338- | OMNIBUS | NA | NA | 329.60 | 7 | 2.81×10 | |
| rs6573910- | ACCAGGTG | 0.573 | 0.672 | 55.00 | 1 | 1.20×10 | |
| rs6573911- | GTTGACCT | 0.115 | 0.101 | 2.81 | 1 | 0.0936 | |
| rs71405867- | GTTGACCG | 0.048 | 0.058 | 2.12 | 1 | 0.1456 | |
| rs1126639- | GTTAACCT | 0.072 | 0.080 | 1.07 | 1 | 0.3017 | |
| rs11539752- | ACCAGGCG | 0.037 | 0.002 | 117.50 | 1 | 2.18×10 | |
| rs10909625- | ACTAGGTG | 0.081 | 0.038 | 48.52 | 1 | 3.26×10 | |
| rs10873219 | GTTAACCG | 0.032 | 0.048 | 7.36 | 1 | 0.0067 | |
| GCCAGGTG | 0.042 | 0.002 | 137.30 | 1 | 1.01×10 | ||
| F_A – haplotype frequency in patients with postsurgical keloids; F_U – haplotype frequency in controls; DF – degrees of freedom. | |||||||