21 June 2022 : Clinical Research
Prognostic Significance of Preoperative Integrated Liver Inflammatory Score in Patients with Hepatocellular Carcinoma
Biao Wu12ABCDEF, Yumeng Wu
2ABC, Xianlin Guo12BCF, Yifei Liu3ACD, Yanping Yue2BCF, Wenjing Zhao2ABG, Jibin Liu2ADG, Xuming Wu4ABC, Aiguo Shen2ACEG*, Suqing Zhang1ACEFG
DOI: 10.12659/MSM.937005
Med Sci Monit 2022; 28:e937005
Table 1 Correlation of ILIS with clinicopathological characteristics.
| Clinical pathological indexes | Training cohort (275 cases) | Validation cohort (157 cases) | ||||
|---|---|---|---|---|---|---|
| Low | High | P | Low | High | P | |
| Age (years) | 0.780 | 0.483 | ||||
| <55 | 59 | 87 | 48 | 34 | ||
| ≥55 | 50 | 79 | 48 | 27 | ||
| Gender | 0.388 | 0.875 | ||||
| Female | 19 | 36 | 21 | 14 | ||
| Male | 90 | 130 | 75 | 47 | ||
| HBV | 0.726 | 0.199 | ||||
| Absent | 43 | 62 | 38 | 18 | ||
| Present | 66 | 104 | 58 | 43 | ||
| Cirrhosis | 0.116 | 0.394 | ||||
| Absent | 40 | 46 | 33 | 17 | ||
| Present | 69 | 120 | 63 | 44 | ||
| Tumour size (cm) | 0.052 | |||||
| ≤5 | 77 | 93 | 71 | 37 | ||
| 5–10 | 29 | 56 | 21 | 17 | ||
| >10 | 3 | 17 | 2 | 6 | ||
| No. of tumour nodules | 0.824 | 0.907 | ||||
| 1 | 93 | 140 | 86 | 55 | ||
| ≥2 | 16 | 26 | 10 | 6 | ||
| Differentiation | ||||||
| Well | 31 | 34 | 22 | 9 | ||
| Moderate | 60 | 78 | 62 | 35 | ||
| Poor | 18 | 54 | 12 | 17 | ||
| Vascular tumor thrombus | 0.943 | 0.097 | ||||
| Absent | 81 | 124 | 77 | 55 | ||
| Present | 28 | 42 | 19 | 6 | ||
| Child-Pugh class | ||||||
| A | 109 | 150 | 95 | 55 | ||
| B | 0 | 16 | 1 | 6 | ||
| BCLC stage | ||||||
| 0 | 14 | 12 | 13 | 12 | ||
| A | 90 | 129 | 70 | 29 | ||
| B | 5 | 25 | 13 | 20 | ||