Role of Serum Creatinine Levels in Prognostic Risk Stratification of Prostate Cancer Patients

22 July 2022 : Database Analysis

Xingbo Gu^1ACDEFG*, Jiaojiao Wu^1BCDEF, Xuefeidan Liu^2AD, Yun Hong^1BCDF, Yaoxi Wu^3AD, Ye Tian^1AD

DOI: 10.12659/MSM.937100

Med Sci Monit 2022; 28:e937100

Background Material and Methods Results Discussion Conclusions References

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Table 2 Odds ratio and 95% confidence interval of 1134 patients with prostate cancer according to the quintiles of serum creatinine.

	Serum creatinine (umol/L)
	Q1: <70.1	Q2: 70.1–76.8	Q3: 76.8–83.4	Q4: 83.4–92.1	Q5: ≥92.1
Model	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)
Model	P	P	P	P	P
Number of patients	222	225	227	229	228
Model1	3.62 (1.73, 7.56)	Ref	3.02 (1.43, 6.39)	3.24 (1.54, 6.80)	3.77 (1.81, 7.83)
Model1	<0.001	Ref	0.004	0.001	<0.001
Model2	3.66 (1.75, 7.67)	Ref	3.00 (1.42, 6.34)	3.27 (1.55, 6.87)	3.76 (1.80, 7.87)
Model2	<0.001	Ref	0.004	0.002	<0.001
Model3	4.87 (1.91, 12.38)	Ref	4.62 (1.81, 11.78)	4.25 (1.69, 10.71)	5.46 (2.16, 13.80)
Model3	0.001	Ref	0.001	0.002	<0.001
crude. adjusted for age and BMI. adjusted for age, BMI, serum albumin, alkaline phosphatase, creatine kinase isoenzyme, serum calcium, serum phosphorus, lactic dehydrogenase, low-density lipoprotein cholesterol, and apolipoprotein A1.

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