10 October 2022 : Database Analysis
Porphyromonas gingivalis Activation of Tumor-Associated Macrophages via DOK3 Promotes Recurrence of Oral Squamous Cell Carcinoma
Chen-xi Li123ABCDEF*, Ying Su4ABCD, Zhong-cheng Gong123ACDG, Hui Liu56ACDDOI: 10.12659/MSM.937126
Med Sci Monit 2022; 28:e937126
Table 1 The GO and KEGG enrich terms.
| Term | Fold enrichment | p-Value | Count |
|---|---|---|---|
| Transcription, DNA-templated | 1.68 | 0.00 | 40 |
| Negative regulation of granulocyte differentiation | 30.72 | 0.00 | 3 |
| Protein targeting to vacuole | 30.72 | 0.00 | 3 |
| Golgi to plasma membrane protein transport | 12.14 | 0.00 | 4 |
| Positive regulation of neuron projection development | 5.52 | 0.00 | 6 |
| Somatic stem cell population maintenance | 6.30 | 0.01 | 5 |
| Blood vessel development | 8.62 | 0.01 | 4 |
| Positive regulation of I-kappaB kinase/NF-kappaB signaling | 3.56 | 0.01 | 7 |
| Lymph node development | 14.46 | 0.02 | 3 |
| activation of MAPKK activity | 7.12 | 0.02 | 4 |
| Positive regulation of type I interferon production | 6.42 | 0.02 | 4 |
| Development of secondary female sexual characteristics | 81.91 | 0.02 | 2 |
| Viral process | 2.47 | 0.03 | 9 |
| Positive regulation of erythrocyte differentiation | 10.24 | 0.03 | 3 |
| Response to tumor necrosis factor | 9.83 | 0.04 | 3 |
| Peptidyl-tyrosine phosphorylation | 3.21 | 0.04 | 6 |
| Endodermal cell differentiation | 9.10 | 0.04 | 3 |
| Glutamate secretion | 8.78 | 0.05 | 3 |
| Hematopoietic progenitor cell differentiation | 4.96 | 0.05 | 4 |
| Creatinine metabolic process | 40.96 | 0.05 | 2 |
| Positive regulation of viral transcription | 8.47 | 0.05 | 3 |
| Transcription from RNA polymerase II promoter | 1.92 | 0.05 | 12 |
| Nucleus | 1.45 | 0.00 | 92 |
| Cytoplasm | 1.38 | 0.00 | 84 |
| Cytosol | 1.52 | 0.00 | 59 |
| Nucleoplasm | 1.57 | 0.00 | 51 |
| Microtubule organizing center | 3.91 | 0.01 | 7 |
| Neuron projection terminus | 19.74 | 0.01 | 3 |
| Apical part of cell | 5.70 | 0.01 | 5 |
| Centrosome | 2.41 | 0.01 | 12 |
| Spindle | 4.24 | 0.01 | 6 |
| Trans-Golgi network membrane | 5.15 | 0.02 | 5 |
| Midbody | 3.98 | 0.02 | 6 |
| Trans-Golgi network | 3.77 | 0.02 | 6 |
| Microtubule | 2.48 | 0.03 | 9 |
| Membrane raft | 2.91 | 0.03 | 7 |
| TAP complex | 57.04 | 0.03 | 2 |
| Recycling endosome | 3.89 | 0.04 | 5 |
| Lysosomal membrane | 2.50 | 0.04 | 8 |
| Protein binding | 1.24 | 0.00 | 127 |
| Receptor signaling protein serine/threonine kinase activity | 9.70 | 0.00 | 6 |
| Transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding | 13.71 | 0.00 | 4 |
| RNA polymerase II distal enhancer sequence-specific DNA binding | 6.59 | 0.01 | 5 |
| Metal ion binding | 1.53 | 0.01 | 37 |
| Poly(A) RNA binding | 1.67 | 0.02 | 22 |
| Activin-activated receptor activity | 85.69 | 0.02 | 2 |
| Transferase activity | 4.46 | 0.03 | 5 |
| Peptide antigen-transporting ATPase activity | 57.13 | 0.03 | 2 |
| TAP1 binding | 42.85 | 0.05 | 2 |
| Tuberculosis | 3.49 | 0.01 | 8 |
| TNF signaling pathway | 4.33 | 0.01 | 6 |
| Focal adhesion | 3.00 | 0.02 | 8 |
| Neurotrophin signaling pathway | 3.86 | 0.02 | 6 |
| Viral myocarditis | 5.42 | 0.04 | 4 |
| MAPK signaling pathway | 2.44 | 0.04 | 8 |
| Apoptosis | 4.99 | 0.04 | 4 |
| Viral carcinogenesis | 2.64 | 0.05 | 7 |