Hemoglobin/Red Blood Cell Distribution Width Ratio in Peripheral Blood Is Positively Associated with Prognosis of Patients with Primary Hepatocellular Carcinoma

16 August 2022 : Clinical Research

Yue Fang^1ABCDEF, Xiaonan Sun^1BC, Lu Zhang^1DE, Yidan Xu^1B, Wen Zhu^2AEFG*

DOI: 10.12659/MSM.937146

Med Sci Monit 2022; 28:e937146

Background Material and Methods Results Discussion Conclusions References

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Table 1 HCC patients (N=252) categorized by HRR and their clinical baseline characteristics.

Variables	All Patients (N 252)		HRR ≤0.987 (N=146)		HRR >0.987 (N=106)		χ2	p Value
Variables	N	%	N	%	N	%	χ2	p Value
Age (mean±SD)	64.67±10.38		64.53±10.17		64.87±10.78		0.276	0.006
Gender
Female	62	24.6	44	30.14	18	16.98	5.730	0.017
Male	190	75.4	102	69.86	88	83.02
Smoke
No	62	24.6	24	16.44	38	35.85	0.380	0.538
Yes	190	75.4	82	83.56	108	64.15
Drink
No	39	23.01	16	10.96	23	21.70	7.060	0.008
Yes	152	76.89	90	89.04	72	78.30
BMI
≤25	196	78.57	138	94.52	60	56.60	52.440	<0.001
>25	54	21.43	8	5.48	46	43.40
CNLC
Ia	18	7.14	18	12.33	0	0	91.784	<0.001
Ib	20	7.94	20	13.70	0	0
IIa	32	12.70	26	17.81	6	5.66
IIb	89	35.32	59	40.41	30	28.30
IIIa	44	17.46	14	9.59	30	28.30
IIIb	19	7.54	9	6.16	10	9.43
IV	30	11.90	0	0	30	28.31
Surgery
Yes	202	80.16	66	45.21	136	93.15	36.836	<0.001
No	50	19.84	40	54.79	10	6.29
WBC
≤8.65×10	214	84.92	88	60.28	126	86.30	0.517	0.472
>8.65×10	38	15.08	18	39.73	20	13.70
BPC
≤3.09×10	232	92.06	96	90.57	136	93.15	0.561	0.454
>3.09×10	20	7.94	10	9.43	10	3.85
Hb (g/dL)
≤11.4 g/dl	24	9.52	10	9.43	14	9.59	9.670	0.002
>11.4 g/dl	228	90.48	96	90.57	132	90.41
AFP (ng/mL)							26.797	<0.001
≤25	75	29.80	13	12.26	62	42.47
>25	177	70.20	92	87.84	83	57.54
HBsAg							0.064	0.801
Negative	46	18.25	19	17.92	27	18.50
Positive	206	81.75	87	82.08	119	81.51
NLR
≤3.85	202	80.16	96	90.57	106	72.60	12.460	<0.001
>3.85	50	19.84	10	9.43	40	27.40
PLR
≤171.09	232	92.06	96	90.57	136	93.15	0.561	0.454
>171.09	20	7.94	10	9.43	10	6.85

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