Performance of Xpert MTB/RIF for Diagnosis of Tuberculosis in HIV-Infected People in China: A Retrospective, Single-Center Study

Guiju Gao; Chunyu Zhu; Yingchu Liu; Siyuan Yang; Jiang Xiao; Hongxin Zhao; Di Yang; Hongyuan Liang; Fang Wang; Liang Wu; Fujie Zhang; Liang Ni

doi:10.12659/MSM.937264

05 October 2022 : Clinical Research

Performance of Xpert MTB/RIF for Diagnosis of Tuberculosis in HIV-Infected People in China: A Retrospective, Single-Center Study

Guiju Gao^1ACDEFG*, Chunyu Zhu^2BCDEF, Yingchu Liu^3BCDEF, Siyuan Yang

^4AB, Jiang Xiao^5ACD, Hongxin Zhao^5CDF, Di Yang^5CDF, Hongyuan Liang^5BCF, Fang Wang^5BDF, Liang Wu^5BCF, Fujie Zhang^5ACEF, Liang Ni^5CF

DOI: 10.12659/MSM.937264

Med Sci Monit 2022; 28:e937264

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Table 3 Sensitivity and specificity of Xpert in different specimens.

	N (%)	Xpert-positive	Sensitivity (95% CI)	Specificity (95% CI)
PTB cases 145
Sputum	25 (18.2%)	12 (84.0%)	80.0 (29.8–98.9)	71.4. (47.6–87.8)
BALF	66 (48.1%)	9 (28.7%)	100.0 (19.7–100.0)	81.2 (69.1–89.5)
EPTB cases 32
CSF	20 (62.5%)	0 (0%)	N/A^*	95.0 (73.1–99.7)
Ascitic fluid	1 (3.1%)	1 (100%)	NA	N/A
Urine	2 (3.2%)	1 (50.0%)	N/A	50.0 (2.6–97.3)
Pleural fluid	3 (9.3%)	2 (66.6%)	N/A	66.6 (12.5–98.2)
BALF – bronchoalveolar lavage fluid; CSF – cerebrospinal fluid; NA – not available. ^* If fewer than 3 positive cases are tested, no calculation will be made.

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Performance of Xpert MTB/RIF for Diagnosis of Tuberculosis in HIV-Infected People in China: A Retrospective, Single-Center Study

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