Performance of Xpert MTB/RIF for Diagnosis of Tuberculosis in HIV-Infected People in China: A Retrospective, Single-Center Study

Guiju Gao; Chunyu Zhu; Yingchu Liu; Siyuan Yang; Jiang Xiao; Hongxin Zhao; Di Yang; Hongyuan Liang; Fang Wang; Liang Wu; Fujie Zhang; Liang Ni

doi:10.12659/MSM.937264

05 October 2022 : Clinical Research

Performance of Xpert MTB/RIF for Diagnosis of Tuberculosis in HIV-Infected People in China: A Retrospective, Single-Center Study

Guiju Gao^1ACDEFG*, Chunyu Zhu^2BCDEF, Yingchu Liu^3BCDEF, Siyuan Yang

^4AB, Jiang Xiao^5ACD, Hongxin Zhao^5CDF, Di Yang^5CDF, Hongyuan Liang^5BCF, Fang Wang^5BDF, Liang Wu^5BCF, Fujie Zhang^5ACEF, Liang Ni^5CF

DOI: 10.12659/MSM.937264

Med Sci Monit 2022; 28:e937264

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Table 4 Comparison of the performance of Xpert, AFB and T-SPOT.TB in the diagnosis of pulmonary tuberculosis when CD4+ <200 cells/mm3.

	Positive	N=149
	Positive	Sensitivity (95% CI, %)	Negative specificity (95% CI, %)
Xpert	43	90.0 (54.1–99.4)	106 84.8 (77.6–90.1)
AFB	27	60.0 (27.3–86.3)^*	122 75.5 (67.3–82.2)
T-SPOT.TB	118	90.0 (54.1–99.4)	31 21.5 (15.2–29.5)^*
^* Statistical differences between the sensitivity or specificity of Xpert, AFB and T-SPOT.TB, chi-square test (χ),

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Performance of Xpert MTB/RIF for Diagnosis of Tuberculosis in HIV-Infected People in China: A Retrospective, Single-Center Study

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