05 October 2022>: Clinical Research
Performance of Xpert MTB/RIF for Diagnosis of Tuberculosis in HIV-Infected People in China: A Retrospective, Single-Center Study
Guiju Gao 1ACDEFG* , Chunyu Zhu 2BCDEF* , Yingchu Liu 3BCDEF* , Siyuan Yang 4AB* , Jiang Xiao 1ACD , Hongxin Zhao 1CDF , Di Yang 1CDF , Hongyuan Liang 1BCF , Fang Wang 1BDF , Liang Wu 1BCF , Fujie Zhang 1ACEF , Liang Ni 1CFDOI: 10.12659/MSM.937264
Med Sci Monit 2022; 28:e937264
Table 4 Comparison of the performance of Xpert, AFB and T-SPOT.TB in the diagnosis of pulmonary tuberculosis when CD4+ <200 cells/mm3.
Positive | N=149 | ||
---|---|---|---|
Sensitivity (95% CI, %) | Negative specificity (95% CI, %) | ||
Xpert | 43 | 90.0 (54.1–99.4) | 106 84.8 (77.6–90.1) |
AFB | 27 | 60.0 (27.3–86.3)* | 122 75.5 (67.3–82.2) |
T-SPOT.TB | 118 | 90.0 (54.1–99.4) | 31 21.5 (15.2–29.5)* |
* Statistical differences between the sensitivity or specificity of Xpert, AFB and T-SPOT.TB, chi-square test (χ), |