29 August 2022 : Database Analysis
Transcriptome Analysis of Peripheral Blood Mononuclear Cells Response in Patients with Severe COVID-19 Reveals Crucial Genes Regulating Protein Ubiquitination
Jinfeng Huang1ABCDEF, Ruobing Li2EF, Jie Cheng3B*, Peilin Zhen1ABDOI: 10.12659/MSM.937532
Med Sci Monit 2022; 28:e937532
Table 2 The molecular complex detection (MCODE) plug-in of Cytoscape was used to process the data downloaded from STRING; specific gene cluster data were exported and presented in a tabular form.
| Cluster | Score | Nodes | Edges | Node IDs |
|---|---|---|---|---|
| 1 | 7 | 8 | 28 | ANAPC1, TRIM21, ASB16, RNF130, FBXO11, UBE2J1, FBXO41, ITCH |
| 2 | 4 | 5 | 10 | RPS18, RPS28, WDR3, RPP21, UTP20 |
| 3 | 4 | 5 | 10 | HCAR2, PCP2, TAS2R19, TAS2R31, TAS2R46 |
| 4 | 4 | 10 | 21 | AGFG1, RAB3D, RAB3A, RAB22A, RABGGTA, FDPS, MVD, PMVK, IPP, MVK |
| 5 | 2 | 3 | 3 | ITGAL, SELPLG, SELP |
| 6 | 1.667 | 3 | 3 | TTC30B, DYNC2H1, TTC30A |
| 7 | 2 | 3 | 3 | CHMP2B, MVB12B, MVB12A |
| 8 | 2 | 3 | 3 | ACTR3C, ARPC1A, ARPC2 |
| 9 | 1.667 | 4 | 4 | ABCB6, TAP1, SLC46A1, ABCB7 |