Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

30 August 2022: Clinical Research

Postoperative Outcomes Following a Modified Method of Surgical Division of the Splenic Pedicle in 719 Patients During Splenectomy for Portal Hypertension: A 12-Year, Retrospective, Single-Center Study

Long Huang 1ABDEFG* , Qingsheng Yu 1DG , Hui Peng 1BCF , Zhou Zhen 2CDF

DOI: 10.12659/MSM.937763

Med Sci Monit 2022; 28:e937763

Table 1 Comparison of the backgrounds of included patients between the 2 groups by PSM analysis.

VariablesUnmatchedPMatchedP
Control group (n=349)Study group (n=370)Control group (n=260)Study group (n=260)
Age (years)32.7±15.033.5±14.70.4732.8±15.033.2±14.80.77
Sex, n (%)0.720.93
 Male199 (57.0)206 (55.7)148 (56.9)147 (56.5)
 Female150 (43.0)164 (44.3)112 (43.1)113 (43.5)
Etiology o cirrhosis, n (%)0.890.93
 HLD cirrhosis267 (76.5)295 (79.7)205 (78.9)204 (78.5)
 HBV cirrhosis62 (17.8)64 (17.3)41 (15.8)46 (17.7)
 HCV cirrhosis9 (2.6)3 (0.8)8 (3.1)3 (1.2)
 Schistosomiasis cirrhosis1 (0.3)2 (0.5)1 (0.4)2 (0.8)
 Alcoholic cirrhosis1 (0.3)2 (0.5)1 (0.4)2 (0.8)
 Autoimmunity cirrhosis7 (2.0)3 (0.8)2 (0.8)2 (0.8)
 Unknown2 (0.6)1 (0.3)2 (0.8)1 (0.4)
Child-Pugh classification, n (%)0.190.65
 A262 (75.1)259 (70.0)194 (74.6)187 (71.9)
 B82 (23.5)107 (28.9)61 (23.5)70 (26.9)
 C5 (1.4)4 (1.1)5 (1.9)3 (1.2)
The size of spleen (mm)
 Longitudinal diameter of spleen180.3±33.0176.5±30.60.11175.8±31.5178.0±31.60.41
 Thickness of spleen69.0±16.872.3±16.40.0170.9±16.870.9±16.10.99
The diameter of portal vein system (cm)
 Portal vein1.5±0.21.4±0.2P1.4±0.21.4±0.20.38
 Splenic vein61.3±0.51.2±0.3P1.3±0.21.3±0.30.43
Preoperative blood examination
 WBC (10/L)2.8±1.73.0±2.00.112.8±1.62.8±1.40.78
 RBC (10/L)3.9±0.74.8±16.80.323.9±0.73.9±0.60.98
 HGB (g/L)108.8±18.1110.0±18.90.38109.2±18.5110.4±19.40.51
 PLT (10/L)51.7±31.449.7±36.00.4250.7±30.349.4±36.70.64
 TBIL (μmol/L)23.2±16.123.4±15.60.8923.7±16.523.6±15.60.95
 ALT (U/L)31.2±16.833.0±32.50.3731.3±18.031.3±16.20.99
 AST (U/L)33.6±17.333.6±22.50.9932.5±15.532.3±13.10.90
 ALB (g/L)37.9±6.337.7±5.00.6238.4±6.537.8±4.80.28
 PT (s)15.0±2.415.5±7.80.3115.1±2.615.0±2.20.61
 PT-INR1.5±2.81.5±1.50.731.6±3.21.5±1.80.67
 D-dimer (mg/L)0.5±1.20.6±0.80.230.5±1.30.6±0.80.74
Variceal hemorrhage history, n (%)0.061
 Yes57 (16.3)81 (21.9)47 (18.1)47 (18.1)
 No292 (83.7)289 (78.1)213 (81.9)213 (81.9)
Operation, n (%)
 Splenectomy only307 (88.0)324 (87.6)0.87227 (87.3)229 (88.1)0.79
 Concomitant pericardial devascularization42 (12.0)46 (12.4)33 (12.7)31 (11.9)
Operation period, n (%)P0.96
 Early-period185 (53.0)103 (27.8)104 (40.0)98 (37.7)
 Intermediate-period101 (28.9)140 (37.8)93 (35.8)106 (40.8)
 Late-period63 (18.1)127 (34.3)63 (24.2)56 (21.5)
PSM – propensity score matching; HLD – hepatolenticular degeneration; HBV – hepatitis B virus; HCV – hepatitis C virus; WBC – white blood cell; RBC – red blood cell; HGB – hemoglobin; PLT – platelet; ALT – alanine aminotransferase; AST – aspartate aminotransferase; ALB – albumin; TBIL – total bilirubin; PT – prothrombin time.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750