07 September 2022 : Clinical Research
Measurement of Serum Levels of 5 Amino Acids and Dimethylamine Using Liquid Chromatography-Tandem Mass Spectrometry in Patients without Septic Associated Acute Kidney Injury and with Septic Associated Acute Kidney Injury Requiring Continuous Renal Replacement Therapy
Patrycja Leśnik1ABCDEFG*, Lidia Łysenko2ADEG, Mariusz G. Fleszar


DOI: 10.12659/MSM.937784
Med Sci Monit 2022; 28:e937784
Table 3 Comparison of the level of amine DMA and selected amino acids in the group with and without AKI.
AKI | p-value* | ||||||
---|---|---|---|---|---|---|---|
Yes (n=13) | No (n=28) | ||||||
Me | Q1 | Q3 | Me | Q1 | Q3 | ||
Arg [umol/L] | 49.0 | 34.3 | 55.0 | 52.8 | 39.6 | 78.0 | 0.189 |
Orn [umol/L] | 10.3 | 3.7 | 32.0 | 7.5 | 5.6 | 16.1 | 0.965 |
ADMA [umol/L] | 0.58 | 0.53 | 0.62 | 0.64 | 0.49 | 0.76 | 0.507 |
SDMA [umol/L] | 1.11 | 0.75 | 1.69 | 1.06 | 0.51 | 1.46 | 0.434 |
DMA [umol/L] | 8.1 | 5.4 | 18.7 | 5.2 | 4.0 | 7.4 | 0.022 |
Cit [umol/L] | 22.0 | 10.7 | 32.1 | 18.5 | 13.6 | 26.2 | 0.734 |
n – number of patients; Me – median; Q1 – lower quartile; Q3 – upper quartile; Arg – L-arginine; Orn – L-Ornithine; ADMA – asymmetric dimethylarginine; SDMA – symmetric dimethylarginine; DMA – dimethylamine; Cit – L-citrulline. * U Mann-Whitney test. |