07 September 2022 : Clinical Research
Measurement of Serum Levels of 5 Amino Acids and Dimethylamine Using Liquid Chromatography-Tandem Mass Spectrometry in Patients without Septic Associated Acute Kidney Injury and with Septic Associated Acute Kidney Injury Requiring Continuous Renal Replacement Therapy
Patrycja Leśnik1ABCDEFG*, Lidia Łysenko2ADEG, Mariusz G. Fleszar


DOI: 10.12659/MSM.937784
Med Sci Monit 2022; 28:e937784
Table 5 The AUC of biomarkers for detection of AKI.
AUC | SE | AUC lower 95% | AUC upper 95% | z | p-value* | |
---|---|---|---|---|---|---|
Arg [μmol/L] | 0.366 | 0.09 | 0.19 | 0.54 | −1.49 | 0.137 |
Orn [μmol/L] | 0.494 | 0.12 | 0.26 | 0.73 | −0.05 | 0.960 |
ADMA [μmol/L] | 0.430 | 0.10 | 0.23 | 0.63 | −0.70 | 0.486 |
SDMA [μmol/L] | 0.580 | 0.10 | 0.39 | 0.77 | 0.84 | 0.403 |
DMA [μmol/L] | 0.732 | 0.09 | 0.55 | 0.91 | 2.55 | 0.011 |
Cit [μmol/L] | 0.536 | 0.105 | 0.33 | 0.741 | 0.341 | 0.733 |
Orn – L-Ornithine; ADMA – asymmetric dimethylarginine; SDMA – symmetric dimethylarginine; DMA – dimethylamine; Cit – L-citrulline; AUC – area under the curve; SE – standard error. * U Mann-Whitney test. |