07 September 2022 : Clinical Research
Measurement of Serum Levels of 5 Amino Acids and Dimethylamine Using Liquid Chromatography-Tandem Mass Spectrometry in Patients without Septic Associated Acute Kidney Injury and with Septic Associated Acute Kidney Injury Requiring Continuous Renal Replacement Therapy
Patrycja Leśnik1ABCDEFG*, Lidia Łysenko2ADEG, Mariusz G. Fleszar


DOI: 10.12659/MSM.937784
Med Sci Monit 2022; 28:e937784
Table 7 The sensitivity, specificity, PPV, NPV, AVV, and LR of DMA and creatinine for detection of CRRT patients.
DMA | CRRT | Creatinine | CRRT | ||
---|---|---|---|---|---|
No (n) | Yes (n) | No (n) | Yes (n) | ||
DMA <14.95 umol/L | 28 | 7 | Creatinine <1.19 mg/dL | 13 | 1 |
DMA ≥14.95 umol/L | 0 | 5 | Creatinine ≥1.19 mg/dL | 15 | 11 |
Sensitivity | 1.000 | Sensitivity | 0.464 | ||
Specificity | 0.417 | Specificity | 0.917 | ||
LR+ | 1.714 | LR+ | 5.571 | ||
LR− | 0.000 | LR− | 0.584 | ||
PPV | 0.800 | PPV | 0.929 | ||
NPV | 1.000 | NPV | 0.423 | ||
ACC | 0.825 | ACC | 0.600 | ||
n – number of patients; DMA – dimethylamine; LR+ – positive likelihood ratio; LR− – negative likelihood ratio; PPV – positive predictive value; NPV – negative predictive value; ACC – accuracy. |