Chemotherapy-Induced Peripheral Neuropathy (CIPN) in Patients Receiving 4-6 Cycles of Platinum-Based and Taxane-Based Chemotherapy: A Prospective, Single-Center Study from Kosovo

Blerim Myftiu; Zylfije Hundozi; Faton Sermaxhaj; Afrim Blyta; Nexhmedin Shala; Fisnik Jashari; Hasime Qorraj Bytyqi; Ekrem Hyseni; Ilir Kurtishi

doi:10.12659/MSM.937856

31 August 2022 : Clinical Research

Chemotherapy-Induced Peripheral Neuropathy (CIPN) in Patients Receiving 4-6 Cycles of Platinum-Based and Taxane-Based Chemotherapy: A Prospective, Single-Center Study from Kosovo

Blerim Myftiu^12ABCDEFG*, Zylfije Hundozi^12ACDF, Faton Sermaxhaj^3ABD, Afrim Blyta^1ACDF, Nexhmedin Shala^12CD, Fisnik Jashari^12C, Hasime Qorraj Bytyqi^4CDF, Ekrem Hyseni^3BC, Ilir Kurtishi^3BC

DOI: 10.12659/MSM.937856

Med Sci Monit 2022; 28:e937856

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Table 4 Sensory nerve conduction studies.

Nerve	Parameter	Pre-treatment value (Mean±SD)	Post-treatment value (Mean±SD)	Significance
Median nerve (N: 97)	Distal latency (ms)	2.2±0.3	2.6±0.4	p<0.001
	Velocity (m/s)	54.6±6.8	49.7±8.7	p<0.001
	Amplitude (μV)	23.7±10.7	12.9±10.1	p<0.001
Ulnar nerve (N: 101)	Distal latency (ms)	1.9±0.3	2.4±1.5	p<0.01
	Velocity (m/s)	54.0±6.9	49.9±10.0	p<0.05
	Amplitude (μV)	13.9±5.4	8.9±8.3	p<0.001
Sural nerve (N: 56)	Distal latency (ms)	2.3±0.3	2.4±0.3	p=0.246
	Velocity (m/s)	53.6±7.4	51.3±8.3	p<0.5
	Amplitude (μV)	16.5±5.5	8.2±6.0	p<0.001
SD – standard deviation.

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Chemotherapy-Induced Peripheral Neuropathy (CIPN) in Patients Receiving 4-6 Cycles of Platinum-Based and Taxane-Based Chemotherapy: A Prospective, Single-Center Study from Kosovo

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