31 August 2022 : Clinical Research
Chemotherapy-Induced Peripheral Neuropathy (CIPN) in Patients Receiving 4-6 Cycles of Platinum-Based and Taxane-Based Chemotherapy: A Prospective, Single-Center Study from Kosovo
Blerim Myftiu12ABCDEFG*, Zylfije Hundozi12ACDF, Faton Sermaxhaj3ABD, Afrim Blyta1ACDF, Nexhmedin Shala12CD, Fisnik Jashari12C, Hasime Qorraj Bytyqi4CDF, Ekrem Hyseni3BC, Ilir Kurtishi3BCDOI: 10.12659/MSM.937856
Med Sci Monit 2022; 28:e937856
Table 5 Motor nerve conduction studies.
| Nerve | Parameter | Pre-treatment value (Mean±SD) | Post-treatment value (Mean±SD) | Significance |
|---|---|---|---|---|
| Median nerve (N: 119) | Distal latency (ms) | 3.2±0.6 | 3.7±0.8 | p<0.001 |
| Velocity (m/s) | 59.2±6.3 | 52.3±7.2 | p<0.001 | |
| Amplitude (mV) | 8.9±2.4 | 6.6±2.4 | p<0.001 | |
| Ulnar nerve (N: 119) | Distal latency (ms) | 2.6±0.4 | 2.8±0.5 | p<0.01 |
| Velocity (m/s) | 61.3±7.0 | 58.2±8.9 | p<0.01 | |
| Amplitude (mV) | 7.6±1.6 | 6.9±2.2 | p<0.01 | |
| Tibial nerve (N: 105) | Distal latency (ms) | 4.5±1.2 | 5.3±1.3 | p<0.001 |
| Velocity (m/s) | 46.0±5.5 | 41.6±5.1 | p<0.001 | |
| Amplitude (mV) | 8.1±3.3 | 5.1±3.4 | p<0.001 | |
| Peroneal nerve (N: 103) | Distal latency (ms) | 4.3±1.1 | 4.5±1.3 | p=0.515 |
| Velocity (m/s) | 49.9±6.7 | 44.1±8.4 | p<0.001 | |
| Amplitude (mV) | 4.6±1.8 | 2.7±1.8 | p<0.001 | |
| SD – standard deviation. | ||||