03 November 2022>: Database Analysis
Association Between Nadir Hematocrit and Severe Acute Kidney Injury After Off-Pump Coronary Artery Bypass Graft Surgery: A Retrospective Cohort Study Based on the MIMIC-IV Database
Yisen Deng 12ACE* , Bo Ma 2DE* , Xuming Wang 12DE* , Xueqiang Fan 2BC , Qiangqiang Nie 12B , Xixi Gao 2B , Yuguang Yang 2CE* , Peng Liu 12CE*DOI: 10.12659/MSM.937878
Med Sci Monit 2022; 28:e937878
Table 2 Relationship between nadir hematocrit and severe acute kidney injury in different models.
Variable | Crude model | Model I | Model II |
---|---|---|---|
OR (95% CIs) | OR (95% CIs) | OR (95% CIs) | |
Hematocrit (%) | |||
1 (Ref) | 1 (Ref) | 1 (Ref) | |
≥5, and | 0.23 (0.1–0.52)*** | 0.24 (0.1–0.54)** | 0.33 (0.13–0.85)* |
≥28, and | 0.18 (0.07–0.43)*** | 0.19 (0.08–0.46)*** | 0.18 (0.06–0.52)** |
≥31 | 0.33 (0.16–0.67)** | 0.35 (0.16–0.76)** | 0.51 (0.19–1.36) |
Trend.test | 0.59 (0.45–0.76)*** | 0.61 (0.46–0.8)*** | 0.68 (0.48–0.95)* |
Crude model: no covariates were adjusted. Model I adjusted for: age and g sex. Model II adjusted for: age, sex, race, BMI, myocardial infarction, congestive heart failure, peripheral vascular disease, rheumatic disease, diabetes with or without complication; systolic BP, diastolic BP, respiratory rate, temperature, glucose, SpO, WBC, platelets, anion gap, lactate, bicarbonate, chloride, sodium, potassium, APTT, SOFA, SAPSII, vasopressin, epinephrine, norepinephrine, and phenylephrine. Ref – reference; AKI – severe acute kidney injury; OR – odds ratio; CI – confidence interval; BMI – body mass index; BP – blood pressure; SpO2 – pulse oxygen saturation; WBC – white blood cell; APTT – activated partial thromboplastin time; SOFA – sequential organ failure assessment; SAPSII – simplified acute physiology score II. * ** *** |