Thyroid-Stimulating Hormone as a Biomarker for Stress After Thyroid Surgery: A Prospective Cohort Study

10 November 2022 : Clinical Research

Hua Hong

^1AB, Jeonghun Lee^1ADE*

DOI: 10.12659/MSM.937957

Med Sci Monit 2022; 28:e937957

Background Material and Methods Results Discussion Conclusions References

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Table 4 Univariate linear mixed-effect regression in all enrolled patients.

Variable	lnTSH
Variable	Estimate	95% CI		P-value
Sex (female)	−0.011	−0.856	0.834	0.9787
Age	0.028	−0.007	0.063	0.1259
Body weight	0.021	−0.009	0.051	0.1608
Height	−0.011	−0.058	0.036	0.6432
T3	−0.058	−0.073	−0.043	< 0.0001
Free T4	−4.895	−5.749	−4.041	< 0.0001
Stress event (present)	3.203	2.169	4.237	< 0.0001
KDSI	0.000	−0.004	0.004	0.8781
SOSS	0.003	−0.026	0.032	0.8390
SOSS-category
High vs low	0.192	−0.499	0.883	0.584
Challenge vs low	0.496	−0.454	1.446	0.304
Fragile vs low	−0.221	−1.219	0.776	0.662
SRRS	−0.001	−0.004	0.002	0.7215
Body weight, during operation	0.018	−0.010	0.046	0.2157
N stage
N1a vs N0	−0.260	−1.037	0.517	0.5131
N1b vs N0	−1.243	−2.359	−0.127	0.0313
Extent of thyroidectomy (total)	−1.552	−2.178	−0.926	<0.0001
Approach (robotic/endoscopic)	0.620	−0.327	1.567	0.2019
Preoperative TSH	0.031	−0.022	0.084	0.246

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