22 April 2023: Clinical Research
Measurement of Serum Ultra-Sensitive Thyroid-Stimulating Hormone Levels to Determine the Risk for Recurrence of Atrial Fibrillation Following Catheter Ablation in 575 Patients from a Single Center
Zhizhao Li 1ABCDEFG* , Xiao-Xia Liu 2AF , Qiong Huang 3F , Yu-Qing Song 1F* , Xue-Yuan Guo 2AF , Chang-Sheng Ma 2A*DOI: 10.12659/MSM.937958
Med Sci Monit 2023; 29:e937958
Table 1 Characteristics based on quartiles of uTSH level.
| Total | uTSH level (miu/L) | |||||||
|---|---|---|---|---|---|---|---|---|
| Q1 (<1.18) | Q2 (1.18–1.84) | p | Q3 (1.84–2.94) | p | Q4 (>2.94) | p | ||
| Participants, n | 575 | 144 | 144 | 144 | 143 | |||
| Age, (years) | 60.46±11.0 | 60.60±11.17 | 60.47±10.26 | 0.92 | 60.31±11.21 | 0.91 | 60.29±11.21 | 0.98 |
| Female, n (%) | 204 (34.70) | 40 | 48 | 0.69 | 54 | 0.19 | 62 | 0.16 |
| BMI, kg/m | 27.68±2.76 | 25.72±4.29 | 27.0±3.65 | 0.01 | 29.36±3.17 | 0.40 | 26.98±3.75 | 0.27 |
| Alcohol, n (%) | 122 (21.22) | 28 | 34 | 0.55 | 31 | 0.76 | 29 | 0.40 |
| Smoking, n (%) | 164 (28.52) | 45 | 35 | 0.62 | 42 | 0.04 | 42 | 0.35 |
| DM, n (%) | 79 (13.74) | 17 | 22 | 0.43 | 18 | 0.48 | 22 | 0.48 |
| CAD, n (%) | 71 (12.35) | 19 | 20 | 0.94 | 15 | 0.58 | 17 | 0.74 |
| REDO, n (%) | 105 (18.26) | 27 | 26 | 0.13 | 19 | 0.46 | 33 | 0.06 |
| HBP, n (%) | 281 (48.87) | 81 | 70 | 0.12 | 74 | 0.68 | 56 | 0.05 |
| Lipid-lowering drugs, n% | 164 (28.52) | 32 | 47 | 0.13 | 45 | 0.46 | 40 | 0.06 |
| LAD (cm) | 40.67±5.36 | 40.35±5.36 | 40.65±5.16 | 0.64 | 40.63±4.78 | 0.97 | 40.01±6.06 | 0.58 |
| LDL-C, mmol/L | 2.75±0.89 | 2.65±40.92 | 2.83±0.84 | 0.10 | 2.80±0.88 | 0.83 | 2.72±0.92 | 0.45 |
| HDL-C, mmol/L | 1.23±0.32 | 1.23±0.26 | 1.22±0.42 | 0.83 | 1.24±0.28 | 0.73 | 1.22±0.29 | 0.55 |
| TG, mmol/L | 1.45±0.96 | 1.41±0.86 | 1.39±0.71 | 0.86 | 1.45±0.81 | 0.50 | 1.57±1.35 | 0.36 |
| CRP, mg/L | 1.96±3.06 | 1.72±3.18 | 2.36±3.36 | 0.10 | 1.73±2.43 | 0.07 | 2.07±3.27 | 0.32 |
| SBP, mmHg | 126.62±17.66 | 126.48±20.45 | 125.5±16.70 | 0.66 | 127.81±15.1 | 0.226 | 127.21±18.53 | 0.77 |
| DBP, mmHg | 78.70±12.0 | 76.97±12.15 | 78.70±11.77 | 0.23 | 80.0±10.69 | 0.33 | 79.48±13.34 | 0.72 |
| FPG, mmol/L | 6.0±1.49 | 6.17±1.76 | 5.92±1.35 | 0.18 | 6.05±1.59 | 0.44 | 5.85±1.18 | 0.21 |
| WBC 10/L | 6.48±2.37 | 6.43±1.57 | 6.42±2.70 | 0.99 | 6.39±1.36 | 0.88 | 0.46±1.75 | 0.68 |
| * Statistically significant value ( Data are presented as n (%), mean±standard deviation; value was concluded from the comparisons among the quintiles. BMI – body mass index; DM – diabetes mellitus; CAD – coronary artery disease; PAF – paroxysmal atrial fibrillation; CAF – persistent atrial fibrillation; REDO – recurrence of atrial fibrillation after radiofrequency catheter ablation; HBP – hypertension; LAD – left atrial diameter; TC – total cholesterol; LDL-C – low-density lipoprotein cholesterol; HDL-C – high-density lipoprotein cholesterol; TG – triglycerides; CRP – C-reactive protein; uTSH – ultra-sensitive thyrotropin; SBP – systolic blood pressure; DBP – diastolic blood pressure; FPG – fasting plasma glucose; WBC – white blood cells; Q – quartile. | ||||||||