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31 October 2022: Clinical Research

hOGG1 rs1052133 Polymorphism and Prostate Cancer Risk: A Chinese Case-Control Study and Meta-Analysis

Hanjiang Xu 123BCDEF , Meng Zhang 123BCDEF , Zongyao Hao 123AC , Chaozhao Liang 123A*

DOI: 10.12659/MSM.938012

Med Sci Monit 2022; 28:e938012

Table 5 Summary risk estimations for the relationship of the hOGG1 polymorphism and prostate cancer risk.

ComparisonSubgroupNPHPZRandomFixed
G vs COverall100.0000.1021.173 (0.969–1.420)1.142 (1.042–1.252)
GG vs CCOverall100.0010.2411.326 (0.828–2.126)1.316 (1.052–1.645)
GC vs CCOverall100.2161.172 (1.032–1.331)1.172 (1.033–1.330)
GC+GG vs CCOverall100.0191.227 (1.003–1.500)1.182 (1.047–1.334)
GG vs GC+CCOverall100.0020.4271.177 (0.788–1.759)1.175 (0.970–1.423)
G vs CAsian40.3061.216 (1.033–1.432)1.217 (1.052–1.409)
GG vs CCAsian40.5411.593 (1.160–2.189)1.593 (1.160–2.187)
GC vs CCAsian40.8500.1161.214 (0.951–1.549)1.215 (0.953–1.550)
GC+GG vs CCAsian40.9331.298 (1.030–1.637)1.299 (1.030–1.638)
GG vs GC+CCAsian40.0570.1741.335 (0.880–2.024)1.290 (1.012–1.645)
G vs CCaucasian30.0000.3171.395 (0.727–2.676)1.238 (1.005–1.526)
GG vs CCCaucasian30.0000.4721.924 (0.323–11.461)1.405 (0.850–2.322)
GC vs CCCaucasian30.0250.1861.430 (0.842–2.429)1.309 (0.993–1.725)
GC+GG vs CCCaucasian30.0010.2421.500 (0.761–2.955)1.313 (1.012–1.705)
GG vs GC+CCCaucasian30.0000.5591.612 (0.325–7.993)1.239 (0.760–2.021)
G vs CMix20.1010.6700.975 (0.709–1.342)1.036 (0.881–1.219)
GG vs CCMix20.3160.8910.971 (0.613–1.540)0.969 (0.615–1.526)
GC vs CCMix20.1170.4381.019 (0.704–1.474)1.084 (0.884–1.327)
GC+GG vs CCMix20.0920.9720.993 (0.674–1.463)1.067 (0.878–1.297)
GG vs GC+CCMix20.4200.7470.932 (0.594–1.461)0.929 (0.593–1.454)
N – number; – -value of heterogeneity test; – -value of Z-test; Mix – from two more races.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750