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29 November 2022: Clinical Research

Sex-Related Differences in Sitagliptin Treatment in Type 2 Diabetes: Results from the PROLOGUE Trial

Xilin Wu 1ABCDEF , Shiming Zhang 1ABCEF , Yingzhu Jin 2ABC , Xun Xiao 3ABCDEF*

DOI: 10.12659/MSM.938030

Med Sci Monit 2022; 28:e938030

Table 2 Baseline characteristics of female participants.

CharacteristicSitagliptin groupConventional groupP-value
Age, years71.04±9.1071.35±8.830.837
Height, cm151.23±5.29150.00±5.700.180
Weight, kg57.95±13.6255.62±10.460.255
Body mass index, kg/m25.15±5.0324.82±4.680.688
Waist circumference, (cm)86.97±11.6886.10±11.970.876
Systolic blood pressure, mmHg130.08±14.74130.88±17.760.766
Diastolic blood pressure, mmHg71.26±11.2469.67±11.640.402
Fasting plasma glucose, mmol/l131.49±35.92133.21±41.930.796
Serum creatinine, μmol/l0.71±0.180.69±0.190.588
Estimated glomerular filtration rate, ml/min/1.73 m66.49±19.0968.78±20.790.491
Hypertension, N (%)60 (78.95%)50 (72.46%)0.362
Dyslipidemia, N (%)58 (76.32%)49 (71.01%)0.468
Cerebral infarction, N (%)10 (13.16%)8 (11.59%)0.776
Cerebral hemorrhage, N (%)1 (1.32%)0 (0.00%)0.339
Myocardial infarction, N (%)7 (9.21%)6 (8.70%)0.914
Arrhythmia, N (%)12 (15.79%)7 (10.14%)0.314
Chronic heart failure, N (%)3 (3.95%)7 (10.14%)0.141
Percutaneous coronary intervention, N (%)13 (17.11%)18 (26.09%)0.188
Coronary artery bypass grafting, N (%)4 (5.26%)1 (1.45%)0.209

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750