Suppression of Tumorigenicity 2 Pro-Inflammatory Biomarker Linking Diabetes Mellitus and Periodontitis: A Pilot Study

Paladugu Devi Navya; Gurumoorthy Kaarthikeyan; Selva Raj J.; Ahmed Alamoudi; Maha A. Bahammam; Bassam Zidane; Hammam Ahmed Bahammam; Sarah Ahmed Bahammam; Ali Abdel-Halim Abdel-Azim Hassan; Mona Awad Kamil; Shilpa Bhandi; A. Thirumal Raj; Shankargouda Patil

doi:10.12659/MSM.938218

15 November 2022 : Clinical Research

Suppression of Tumorigenicity 2 Pro-Inflammatory Biomarker Linking Diabetes Mellitus and Periodontitis: A Pilot Study

Paladugu Devi Navya^1CDF*, Gurumoorthy Kaarthikeyan^1CEF, Selva Raj J.^2BCDE, Ahmed Alamoudi^3AEF, Maha A. Bahammam^45CEF, Bassam Zidane^6BDE, Hammam Ahmed Bahammam

^7BDF, Sarah Ahmed Bahammam^8CEF, Ali Abdel-Halim Abdel-Azim Hassan^9CDE, Mona Awad Kamil^10BDE, Shilpa Bhandi^1112BEF, A. Thirumal Raj

^13CEF, Shankargouda Patil^1415ACE

DOI: 10.12659/MSM.938218

Med Sci Monit 2022; 28:e938218

Authors information Article notes Copyright and License information

¹Department of Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India
²Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India
³Department of Oral Biology, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia
⁴Department of Periodontology, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia
⁵Executive Presidency of Academic Affairs, Saudi Commission for Health Specialties, Riyadh, Saudi Arabia
⁶Department of Restorative Dentistry, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia
⁷Department of Pediatric Dentistry, College of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia
⁸Department of Pediatric Dentistry and Orthodontics, College of Dentistry, Taibah University, Medina, Saudi Arabia
⁹Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia
¹⁰Department of Preventive Dental Science, College of Dentistry, Jazan University, Jazan, Saudi Arabia
¹¹ College of Dental Medicine, Roseman University of Health Sciences, Jordan, USA
¹²Department of Cariology, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India
¹³Department of Oral Pathology and Microbiology, Sri Venkateswara Dental College and Hospital, Chennai, India
¹⁴Centre of Molecular Medicine and Diagnostics (COMManD), Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India

^*Corresponding Author: Paladugu Navya, e-mail: [email protected]
^*Corresponding Author: Shankargouda Patil, e-mail: [email protected]

^AStudy design/planning
^BData collection/entry
^CData analysis/statistics
^DData interpretation
^EPreparation of manuscript
^FLiterature analysis/search

Background Material and Methods Results Discussion Conclusions References

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Table 3 Comparison of suppression of tumorigenicity 2 (ST2) levels in gingival crevicular fluid (GCF) by sex and group.

Serial no.	Sex	Group	Mean	P value
1	Male	1	211.02	0.098 (NS)
		2	471.10
		3	566.93
2	Female	1	315.52	0.078 (NS)
		2	423.38
		3	550.80
Group 1, healthy; group 2, periodontitis; group 3, periodontitis with diabetes mellitus. NS – not significant. When the value is more than 0.05, there is no statistical difference between the sex and ST2 expression.

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Suppression of Tumorigenicity 2 Pro-Inflammatory Biomarker Linking Diabetes Mellitus and Periodontitis: A Pilot Study

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