26 August 2022: Clinical Research
Effect of Positive End-Expiratory Pressure (PEEP) Titration in Elderly Patients Undergoing Lobectomy
Wenyu Yao 1AE* , Bo Yang 2B , Wenlong Wang 3B , Qian Han 1D , Fenghai Liu 4D , Shiqiang Shan 1G , Chao Wang 1E , Mengliang Zheng 1FDOI: 10.12659/MSM.938225
Med Sci Monit 2022; 28:e938225
Table 4 Comparison of gas exchange indexes.
| Index | Group | T1 | T2 | T3 |
|---|---|---|---|---|
| PaO (mmHg) | Group O | 270.56±32.03 | 202.28±59.66# | 238.18±36.57# |
| Group C | 261.91±35.54 | 112.23±8.74* | 225.42±41.31# | |
| PaCO (mmHg) | Group O | 40.85±2.08 | 42.2±1.59 | 42.58±1.56 |
| Group C | 40.72±2.41 | 42.26±1.71 | 42.79±1.40 | |
| VD/VT | Group O | 0.07±0.03 | 0.07±0.02 | 0.11±0.04# |
| Group C | 0.08±0.04 | 0.08±0.03 | 0.12±0.04# | |
| Compared with group O, * # Regarding the gas exchange indices, at the completion of one-lung ventilation titration (T2), PaO in group O was significantly higher than that in group C (202.28±59.66 mmHg vs 112.23±8.74 mmHg). Compared with time of bilateral ventilation (T1), T2, and 10 min after the resumption of bilateral ventilation after intubation (T3) decreased significantly in both groups. The value of void volume/tidal volume ratio (VD/VT) in group C was significantly higher than that in group O at T2 and T3 (0.09±0.03 vs 0.07±0.02 and 0.13±0.04 vs 0.11±0.04, respectively). Compared with at T1, the VD/VT of the 2 groups were significantly higher at T3. | ||||