21 January 2023: Database Analysis
NFYAv1 is a Tumor-Promoting Transcript Associated with Poor Prognosis of Hepatocellular Carcinoma
Zigang Li 1ABCDEF* , Chengshan You 2ADF , Jun Huang 1CD , Ming Zhang 1BEDOI: 10.12659/MSM.938410
Med Sci Monit 2023; 29:e938410
Table 2 GO and KEGG analysis of NFYAv2-correlated genes in HCC cases in TCGA-LIHC.
| Ontology | ID | Description | Gene ratio | Bg ratio | p value | p. adjust | q value |
|---|---|---|---|---|---|---|---|
| BP | GO: 0016570 | Histone modification | 46/412 | 454/18670 | 4.90e-18 | 1.66e-14 | 1.51e-14 |
| BP | GO: 0016569 | Covalent chromatin modification | 46/412 | 474/18670 | 2.66e-17 | 3.57e-14 | 3.24e-14 |
| BP | GO: 0018205 | Peptidyl-lysine modification | 42/412 | 397/18670 | 3.17e-17 | 3.57e-14 | 3.24e-14 |
| CC | GO: 0070469 | Respiratory chain | 20/422 | 100/19717 | 2.90e-14 | 1.30e-11 | 1.01e-11 |
| CC | GO: 0098803 | Respiratory chain complex | 17/422 | 85/19717 | 2.54e-12 | 5.69e-10 | 4.42e-10 |
| CC | GO: 0005746 | Mitochondrial respiratory chain | 17/422 | 88/19717 | 4.60e-12 | 6.87e-10 | 5.34e-10 |
| MF | GO: 0042393 | Histone binding | 25/414 | 197/17697 | 6.22e-12 | 3.01e-09 | 2.43e-09 |
| MF | GO: 0003713 | Transcription coactivator activity | 29/414 | 319/17697 | 4.78e-10 | 1.16e-07 | 9.36e-08 |
| MF | GO: 0061733 | Peptide-lysine-N-acetyltransferase activity | 13/414 | 66/17697 | 3.46e-09 | 5.20e-07 | 4.20e-07 |
| KEGG | hsa04714 | Thermogenesis | 27/177 | 231/8076 | 6.08e-13 | 1.22e-10 | 1.08e-10 |
| KEGG | hsa05020 | Prion disease | 28/177 | 273/8076 | 5.57e-12 | 4.28e-10 | 3.81e-10 |
| KEGG | hsa00190 | Oxidative phosphorylation | 20/177 | 133/8076 | 7.18e-12 | 4.28e-10 | 3.81e-10 |