12 December 2022>: Clinical Research
Preoperative Biologics Exposure Predisposes Ulcerative Colitis Patients to a Distinct Delayed Postoperative Ileus Syndrome After Colectomy
Zhenyu Yuan ABCEF , Liying Cui ACD , Suting Liu BCD , Wenhao Zhang AEF , Qing Ji ADE*DOI: 10.12659/MSM.938412
Med Sci Monit 2022; 28:e938412
Table 1 Characteristics of the enrolled patients (n=263).
Characteristics | |
---|---|
Age at surgery (y) | 43.2±13.7 |
Gender (Male), n (%) | 145 (55.1) |
Body mass index (kg/m) | 19.1±2.9 |
Disease duration (m) | 33 (1–186) |
Disease subtype (E2: E3), n (%) | 121: 142 (45: 54) |
Previous abdominal surgery, n (%) | 13 (4.9) |
Preoperative medication, n (%) | |
5-ASA | 98 (37.3) |
Immunomodulators | 35 (13.3) |
Steroids | 183 (69.6) |
Biologics | 65 (24.7) |
Sessions/courses of biologics | 3 (1–13) |
Current or prior Smoking, n (%) | 39 (12.2) |
Indications of surgery (fulminant disease/treatment failure/neoplasia) | 49/208/6 |
Emergent surgery, n (%) | 39 (14.8) |
Laparoscopic approach, n (%) | 219 (83.3) |
Operation type, n (%) | |
Total proctocolectomy and pouch | 196 (74.5) |
Subtotal colectomy | 67 (25.5) |
Intraoperative blood loss (mL) | 100 (30–200) |
Operative time (min) | 253.8±58.0 |
Infectious complications, n (%) | 43 (16.3) |
Postoperative length of stay (d) | 12 (3–42) |
Prolonged POI, n (%) | 31 (11.8) |
Delayed POI, n (%) | 26 (9.9) |