25 January 2023 : Clinical Research
Changes in Heparin-Binding Protein, Procalcitonin, and C-Reactive Protein Within the First 72 Hours Predict 28-Day Mortality in Patients Admitted to the Intensive Care Unit with Septic Shock
Hui Xue1ABCDEFG, Feng Yu1AFG*DOI: 10.12659/MSM.938538
Med Sci Monit 2023; 29:e938538
Table 1 Baseline characteristics of survivors and non-survivors following septic shock.
| Characteristics | Non-survivors (n=64) | Survivors (n=82) | P value |
|---|---|---|---|
| Age (years)* | 66.50 (53.00, 72.00) | 64.5 (53.00, 72.00) | 0.698 |
| Male (n, %) | 34 (53.1%) | 45 (54.9%) | 0.833 |
| Length of ICU stay (days)* | 12.50 (9.00, 15.00) | 11.50 (8.00, 15.00) | 0.214 |
| Comorbidities (n, %) | |||
| Hypertension | 29 (45.3%) | 34 (41.5%) | 0.641 |
| Diabetes | 12 (18.7%) | 16 (19.5%) | 0.908 |
| Coronary heart disease | 23 (35.9%) | 29 (35.4%) | 0.943 |
| Cerebrovascular disease | 10 (15.6%) | 16 (19.5%) | 0.542 |
| COPD | 9 (14.1%) | 10 (12.2%) | 0.739 |
| Cirrhosis | 4 (6.2%) | 6 (7.3%) | 0.800 |
| Chronic kidney disease | 12 (18.7%) | 11 (13.4%) | 0.380 |
| Trauma | 6 (9.4%) | 9 (11.0%) | 0.752 |
| Infection subclass (n, %) | |||
| Pulmonary infection | 41 (64.1%) | 55 (67.1%) | 0.704 |
| Intra-abdominal infection | 18 (28.1%) | 21 (25.6%) | 0.723 |
| Urinary tract infection | 13 (20.3%) | 16 (19.5%) | 0.904 |
| Skin/soft tissue | 3 (4.7%) | 5 (6.1%) | 0.710 |
| Bloodstream | 34 (53.1%) | 30 (36.6%) | 0.046 |
| Other | 5 (7.8%) | 9 (11.0%) | 0.520 |
| WBC (10/L)* | 12.15 (7.67, 19.45) | 10.50 (7.30, 15.53) | 0.311 |
| SOFA (mean±SD) | 10.70±2.96 | 10.05±0.90 | 0.060 |
| APACHE II (mean±SD) | 21.06±2.97 | 19.77±0.92 | 0.000 |
| * Median (interquartile range); EICU – Emergency Intensive Care Unit; COPD – Chronic Obstructive Pulmonary Disease; WBC – white blood cell counts; SOFA – Sequential Organ Failure Assessment; APACHE II – Acute Physiology and Chronic Health Evaluation. | |||