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28 March 2023: Database Analysis

A Novel Immune-Related Signature to Predict Prognosis and Immune Infiltration of Cervical Cancer

Yun Lin 1ABCDE , Rendong Zhang 2BCD , Hongchao Pan 1CDG , Yaochen Li 1AEG*

DOI: 10.12659/MSM.938660

Med Sci Monit 2023; 29:e938660

Table 1 Univariate and multivariate Cox regression analyses for prognostic factors and overall survival of cervical cancer.

CharacteristicTotal (N)Univariate analysisMultivariate analysis
Hazard ratio (95% CI)p valueHazard ratio (95% CI)p value
Age (>50 vs ≤50)2930.776 (0.488–1.234)0.284
BMI (≤24 vs >24)2540.509 (0.295–0.878)0.509 (0.262–0.987)
Clinical stage (stage I&II vs stage III&IV)2872.369 (1.457–3.854)1.637 (0.735–3.644)0.228
M stage (M0 vs M1)2453.651 (1.226–10.872)2.950 (0.828–10.507)0.095
N stage (N0 vs N1)2502.844 (1.446–5.593)2.675 (1.131–6.325)
Histological type (squamous vs adenosquamous cell carcinoma)2931.713 (0.234–12.529)0.596
Immune-related gene signature (low vs high)2933.520 (2.107–5.882)3.291 (1.609–6.729)
CI – confidence interval; BMI – body mass index.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750