28 March 2023>: Database Analysis
A Novel Immune-Related Signature to Predict Prognosis and Immune Infiltration of Cervical Cancer
Yun Lin 1ABCDE , Rendong Zhang 2BCD , Hongchao Pan 1CDG , Yaochen Li 1AEG*DOI: 10.12659/MSM.938660
Med Sci Monit 2023; 29:e938660
Table 1 Univariate and multivariate Cox regression analyses for prognostic factors and overall survival of cervical cancer.
Characteristic | Total (N) | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|---|
Hazard ratio (95% CI) | p value | Hazard ratio (95% CI) | p value | ||
Age (>50 vs ≤50) | 293 | 0.776 (0.488–1.234) | 0.284 | ||
BMI (≤24 vs >24) | 254 | 0.509 (0.295–0.878) | 0.509 (0.262–0.987) | ||
Clinical stage (stage I&II vs stage III&IV) | 287 | 2.369 (1.457–3.854) | 1.637 (0.735–3.644) | 0.228 | |
M stage (M0 vs M1) | 245 | 3.651 (1.226–10.872) | 2.950 (0.828–10.507) | 0.095 | |
N stage (N0 vs N1) | 250 | 2.844 (1.446–5.593) | 2.675 (1.131–6.325) | ||
Histological type (squamous vs adenosquamous cell carcinoma) | 293 | 1.713 (0.234–12.529) | 0.596 | ||
Immune-related gene signature (low vs high) | 293 | 3.520 (2.107–5.882) | 3.291 (1.609–6.729) | ||
CI – confidence interval; BMI – body mass index. |