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01 February 2023: Lab/In Vitro Research

Neutrophil-to-Platelet Ratio in Patients with Ulcerative Colitis Treated with Infliximab or Vedolizumab: A Retrospective, Single-Center Study in Poland

Marcin Warpechowski 1CD* , Jędrzej Warpechowski 2AEF , Anita Pieńkowska 2BEF , Szymon Sagała 2BEF , Robert Milewski 1CDE

DOI: 10.12659/MSM.938827

Med Sci Monit 2023; 29:e938827

Table 1 General characteristics of the study group of ulcerative colitis patients treated with Infliximab or Vedolizumab. (Word 2016, Microsoft Office).

All patients
Number of patients35
Gender: male/female27/8
Age at diagnosis, median (interquartile range)28 (18–36) years
Age at start of therapy, median (interquartile range)
 Vedolizumab23 (18–31) years
 Infliximab32 (21–38) years
Disease duration, median (interquartile range)7 (4–10) years
UC location: proctitis/left-sided/pancolitis2/15/18
Contaminant therapies, n%
 Immunomodulators9 (25.7%)
 Corticosteroids6 (17.14%)
 Mesalamine21 (60%)
 Sulfasalazine2 (5.7%)
Partial Mayo score, median (interquartile range)7 (6–8)
WBC (/μl), median (interquartile range)7950 (6025–9380)
Platelet (×10/μl), median (interquartile range)257 (221–301)
Neutrophils (×10/μl), median (interquartile range)4.718 (3.217–5.55)
Hemoglobin (g/dl), median (interquartile range)13.25 (11.7–14.8)
CRP (mg/l), median (interquartile range)2.75 (1.2–6.4)
MPV (fl), median (interquartile range)9.9 (9.3–10.8)
Neutrophil-to-platelet ratio, median (interquartile range)17.98 (14.16–21.40)
UC – ulcerative colitis, WBC – white blood cells, CRP – C-reactive protein, MPV – mean platelet volume, μl – microliters, g/dl – grams per deciliter, mg/l – milligrams per liter, fl – femtoliters.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750