Exploration of Perioperative Sleep Disturbance in 208 Patients Undergoing Non-Cardiac Surgery: Protocol for a Prospective Cohort Study

05 April 2023: Clinical Research

Jiaojiao Yang ^1BEF , Xue Han ^1B , Xiao Liu ^1C , Ying Cao ^1D , Kang Yu ^1D , Lei Liu ^2C , Huihui Miao ^1AEG* , Tianzuo Li ^1AE*

DOI: 10.12659/MSM.938832

Med Sci Monit 2023; 29:e938832

Table 1 The schedule of study design.

Study component	Visit 1	Visit 2	Visit 3	Visit 4
Time	1 day before surgery	Night 1	Night 3	Night 5
Eligibility screen	×
Randomization	×
Informed consent	×
Demographic characteristics	×
PSQI	×	×	×	×
Wearable EEG Sleep Monitor	×	×	×	×
SAS score	×
SDS score	×
VAS score	×	×	×
Surgical classification		×
Operation time (min)		×
Infusion (mL)		×
Urine volume (mL)		×
Bleeding (mL)		×
Sufentanil (ug)		×
Remifentanil (ug)		×
Midazolam (mg)		×
Dexmedetomidine (ug)		×
Extubation time (min)		×
Duration stayed in PACU (min)		×
Postoperative fever		×	×
PONV		×	×
PCIA		×	×
First ambulation after operation (h)		×	×
Satisfaction of ward environment				×
Adverse events	×	×	×	×
SQI – Pittsburgh Sleep Quality Index; SAS – self-rating anxiety scale; SDS – self-rating depression scale; VAS – visual analog scale; PONV – postoperative nausea and vomiting; PCIA – patient-controlled intravenous analgesia; PACU – Post Anesthesia Care Unit.