05 April 2023 : Clinical Research
Exploration of Perioperative Sleep Disturbance in 208 Patients Undergoing Non-Cardiac Surgery: Protocol for a Prospective Cohort Study
Jiaojiao Yang1BEF, Xue Han1B, Xiao Liu1C, Ying Cao1D, Kang Yu1D, Lei Liu2C, Huihui Miao1AEG*, Tianzuo Li1AEDOI: 10.12659/MSM.938832
Med Sci Monit 2023; 29:e938832
Table 1 The schedule of study design.
| Study component | Visit 1 | Visit 2 | Visit 3 | Visit 4 |
|---|---|---|---|---|
| Time | 1 day before surgery | Night 1 | Night 3 | Night 5 |
| Eligibility screen | × | |||
| Randomization | × | |||
| Informed consent | × | |||
| Demographic characteristics | × | |||
| PSQI | × | × | × | × |
| Wearable EEG Sleep Monitor | × | × | × | × |
| SAS score | × | |||
| SDS score | × | |||
| VAS score | × | × | × | |
| Surgical classification | × | |||
| Operation time (min) | × | |||
| Infusion (mL) | × | |||
| Urine volume (mL) | × | |||
| Bleeding (mL) | × | |||
| Sufentanil (ug) | × | |||
| Remifentanil (ug) | × | |||
| Midazolam (mg) | × | |||
| Dexmedetomidine (ug) | × | |||
| Extubation time (min) | × | |||
| Duration stayed in PACU (min) | × | |||
| Postoperative fever | × | × | ||
| PONV | × | × | ||
| PCIA | × | × | ||
| First ambulation after operation (h) | × | × | ||
| Satisfaction of ward environment | × | |||
| Adverse events | × | × | × | × |
| SQI – Pittsburgh Sleep Quality Index; SAS – self-rating anxiety scale; SDS – self-rating depression scale; VAS – visual analog scale; PONV – postoperative nausea and vomiting; PCIA – patient-controlled intravenous analgesia; PACU – Post Anesthesia Care Unit. | ||||






