11 April 2023>: Clinical Research
Intraoperative Hypotension and Its Association with Postoperative Acute Kidney Injury in Patients Undergoing Pancreaticoduodenectomy: A 5-Year, Single-Center, Retrospective Cohort Study
Zbigniew Putowski 1ABCDEF* , Karolina Majewska 12ABCDE , Karol Gruca 1ABCD , Aleksandra Zimnoch 1ABC , Anna Szczepańska 3DEF , Łukasz J. Krzych 3ABCDE , Beata Jabłońska 4DEF , Sławomir Mrowiec 4DEFDOI: 10.12659/MSM.938945
Med Sci Monit 2023; 29:e938945
Table 1 Patient-related factors associated with postoperative AKI.
Variable | Postoperative AKI (−) | Postoperative AKI (+) | P value |
---|---|---|---|
Age (yr) | 63.5 (57.0–69.0) | 67.0 (61.0–73.0) | |
Male (yes/no) | 123 (50.6) | 31 (53.4) | 0.7 |
BMI (kg·m) | 25.1 (22.3–28.0) | 25.8 (22.5–28.4) | 0.3 |
Neoadjuvant chemotherapy (yes/no) | 14 (6.0) | 7 (12.3) | 0.1 |
Chronic kidney disease (yes/no) | 2 (0.9) | 2 (3.7) | 0.2 |
Coronary heart disease (yes/no) | 16 (6.9) | 9 (16.4) | |
Diabetes mellitus (yes/no) | 63 (26.8) | 13 (23.6) | 0.8 |
Preoperative hemoglobin (g dL) | 13.4 (12.5–14.3) | 12.9 (12.2–13.9) | 0.17 |
Preoperative creatinine (mg dL) | 0.86 (0.77–0.98) | 0.88 (0.78–0.98) | 0.6 |
Chronic arterial hypertension (yes/no) | 130 (55.8) | 38 (69.1) | 0.0725 |
ACEI/ARB (yes/no) | 70 (30.4) | 24 (44.4) | |
Beta-blocker (yes/no) | 86 (37.4) | 22 (40.7) | 0.6 |
Calcium antagonist (yes/no) | 30 (13.0) | 6 (11.1) | 0.7 |
Diuretics (yes/no) | 30 (13.0) | 9 (16.7) | 0.5 |
I (yes/no) | 4 (1.6) | 0 (0.0) | 1 |
II (yes/no) | 120 (49.4) | 20 (34.5) | |
III (yes/no) | 115 (47.3) | 38 (65.5) | |
IV (yes/no) | 3 (1.2) | 0 (0.0) | 1 |
CCI (points) | 4 (3–5) | 5 (4–6) | |
RCRI (points) | 1 (1–2) | 1 (1–2) | 0.6 |
Premedication (yes/no) | 188 (77.4) | 39 (67.2) | 0.1 |
Preinduction MAP (mmHg) | 102.0 (92.1–110.8) | 107.8 (96.7–117.7) | |
Continuous variables are expressed as median and interquartile range (in brackets). Qualitative variables are expressed as absolute values and/or percent (in brackets). BMI – body mass index; CCI – Charlson Comorbidity Index; ACEI/ARB – angiotensin-converting enzyme inhibitors/angiotensin receptor blockers; MAP – mean arterial pressure; AKI – acute kidney injury; RCRI – revised cardiac risk index. |