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03 April 2023: Clinical Research

Evaluation of a Previously Developed Predictive Model for Infective Endocarditis in 320 Patients Presenting with Fever at 4 Centers in Japan Between January 2018 and December 2020

Shun Yamashita 1ABCDEF* , Masaki Tago 1ACDEF , Yoshinori Tokushima 1BCDF , Yukinori Harada 2ABD , Yudai Suzuki 2ABCD , Yuki Aizawa 2ABCD , Taiju Miyagami 3ABCD , Fumiaki Sano 3ABCD , Yosuke Sasaki 4ABCD , Fumiya Komatsu 4ABCD , Taro Shimizu 2BCD , Toshio Naito 3BCD , Yoshihisa Urita 4BCD , Shu-ichi Yamashita 1BCDE

DOI: 10.12659/MSM.939640

Med Sci Monit 2023; 29:e939640

Table 5 Validation of the prediction model with the cut-off points determined in the present study and the original study.

Statistics for 3 cutoff pointsUsing cutoff value of the present studyUsing cutoff value of the original study
Cutoff value for scores−1.75−1.68
Probability* 1516
Sensitivity9090
Specificity4952
Positive predictive value5253
Negative predictive value9090
Cutoff value for scores−0.72−1.1
Probability* 3325
Sensitivity8687
Specificity6458
Positive predictive value5955
Negative predictive value8888
Cutoff value for scores3.15−0.38
Probability* 9640
Sensitivity3282
Specificity9067
Positive predictive value6660
Negative predictive value6987
* Calculated as the probability of a prediction model for IE among patients with undiagnosed fever.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750