26 May 2023 : Laboratory Research
Preparation, Physicochemical Properties, and Structural Characterization of Resistant Starch-Aspirin-Loaded Microspheres
Qilin Zhou12ACDE, Dan Feng3DFG, Haiyan Yang3CD, Fei Luo3B, Yi Zhou2C, Zizhen Yin2B, Yongjian Sun
4AG, Bin Han13EFG*
DOI: 10.12659/MSM.939711
Med Sci Monit 2023; 29:e939711
Table 1 Single-factor experimental design.
| Single factor | Gradient | Other factors | ||||
|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | ||
| Core: wall Ratio | 1: 1 | 1: 2 | 1: 3 | 1: 4 | 1: 5 | Chitosan concentration=2%;Drying inlet temperature=130°C;Spray drying injection rate=6 mL/min |
| Chitosan concentration | 1% | 2% | 3% | 4% | 5% | Core: wall ratio=1: 2;Drying inlet temperature=130°C;Spray drying injection rate=6 mL/min |
| Drying inlet temperature (°C) | 120 | 125 | 130 | 135 | 140 | Core: wall ratio=1: 2;Chitosan concentration=2%;Spray drying injection rate=6 mL/min |
| Spray drying injection rate (mL/min) | 4 | 5 | 6 | 7 | 8 | Core: wall ratio=1: 2;Chitosan concentration=2%;Drying inlet temperature=130°C |