Influence of Umbilical Cord Blood Biochemical Parameters and Disease Condition on the Expression of the TSG-6 Gene in Umbilical Mesenchymal Stem Cells

Aleksandra Ozygała; Gabriela Wojciechowska; Kinga Traczyk; Dominika Przywara; Alicja Petniak; Rafał Szymanowski; Agnieszka Wilińska; Arkadiusz Krzyżanowski; Anna Kwaśniewska; Bartosz J. Płachno; Paulina Gil-Kulik; Janusz Kocki

doi:10.12659/MSM.939716

14 June 2023 : Clinical Research

Influence of Umbilical Cord Blood Biochemical Parameters and Disease Condition on the Expression of the TSG-6 Gene in Umbilical Mesenchymal Stem Cells

Aleksandra Ozygała^1ABDEFG, Gabriela Wojciechowska^1BDEF, Kinga Traczyk^1BDEF, Dominika Przywara^23ABDEF, Alicja Petniak

^2BDEF, Rafał Szymanowski^2BE, Agnieszka Wilińska^2BE, Arkadiusz Krzyżanowski^4BF, Anna Kwaśniewska^4BF, Bartosz J. Płachno^5EF, Paulina Gil-Kulik

^6ABCDEF*, Janusz Kocki^2ADEG

DOI: 10.12659/MSM.939716

Med Sci Monit 2023; 29:e939716

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Table 3 Correlations between the parameters studied in the entire study group (n=45).

Parameter	RQ IL1A	RQ IL1B	RQ IL1R1	RQ IL2	RQ IL6	RQ IL6R	RQ TSG-6
RQ	1.000	^*	^*	−^*	^*	−0.280	0.235
RQ	^*	1.000	0.074	−0.190		−0.291	^*
RQ	^*	0.074	1.000	−0.194		^*	^*
RQ	−^*	−0.190	−0.194	1.000	−0.286	0.260	0.149
RQ	^*	^*	^*	−0.286	1.000	−^*	0.305
RQ	−0.280	−0.291	^*	0.260	−^*	1.000	0.034
RQ	0.235	^*	^*	0.149	0.305	0.034	1.000
Mother’s age	^*	0.256	−0.008	−0.265	0.233	−^*	0.183
Number of pregnancies	−0.211	0.102	−0.151	0.184	−0.165	−0.078	0.015
Number of deliveries	−0.161	0.124	−0.075	0.224	−0.058	−0.179	0.183
Weeks of gestation	0.114	0.153	−0.119	−0.117	0.168	−0.280	−0.141
Newborn weight	0.073	0.143	−0.010	−0.023	0.183	−0.243	−0.167
pH	−0.045	−0.086	0.123	0.362	−0.054	0.084	^*
pCO	0.139	0.116	−0.062	−^*	^*	−0.119	−0.280
PO	−0.096	0.065	−0.165	0.207	−^*	0.072	0.151
cHCO	0.166	0.027	0.118	−0.008	0.248	−0.208	0.176
WBC	0.163	0.123	−0.084	0.032	0.026	−0.013	0.002
RBC	−0.005	0.142	−0.188	−0.130	0.012	−0.076	−0.242
HGB	0.285	0.152	0.233	−0.262	^*	−0.134	0.132
HCT	0.076	0.150	0.100	−0.178	0.178	−0.056	−0.022
MCV	0.197	−0.009	0.314	−0.265	0.219	−0.048	0.260
MCH	0.277	0.015	0.277	−0.179	^*	−^*	^*
MCHC	^*	0.005	^*	0.042	0.287	−^*	^*
PLT	0.126	0.226	−0.077	^*	−0.138	^*	0.363
^* pH – potential of hydrogen; pO – partial pressure of oxygen; pCO – partial pressure of carbon dioxide; WBC – white blood cell count; RBC – red blood cell count; HGB – hemoglobin; HCT – hematocrit; MCV – mean corpuscular volume; MCH – mean corpuscular hemoglobin; MCHC – mean corpuscular hemoglobin concentration; PLT – platelet count; RQ – level of relative expression; SD – standard deviation; SE – standard error.

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Influence of Umbilical Cord Blood Biochemical Parameters and Disease Condition on the Expression of the TSG-6 Gene in Umbilical Mesenchymal Stem Cells

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