B-Type Natriuretic Peptide Can Distinguish Ischemic Stroke Subtypes Better than Other Cardiac Biomarkers

19 June 2023: Clinical Research

Ping Liang ^12ABCEF* , Shuang Han ^12ADG* , Yucen Jiang ^12B , Huikai Miao ^3BD* , Xiaowei Qi ^12ADG

DOI: 10.12659/MSM.939829

Med Sci Monit 2023; 29:e939829

Table 6 Influential factors of cardioembolism ischemic stroke.

Variables	Univariate analysis		Multivariate analysis
Variables	P	Crude OR (95% CI)	P	Adjusted OR (95% CI)
No history of hypertension		0.10 (0.22–0.48)	0.169	0.15 (0.46–1.39)
No history of diabetes	0.032	0.16 (0.39–0.92)	0.761	0.24 (0.83–2.81)
BNP		1.03 (1.05–1.06)		1.02 (1.04–1.06)
UA	0.007	0.99 (1.00–1.00)	0.002	0.98 (0.99–1.00)
Apo-A1		0.01 (0.05–0.19)	0.006	0.01 (0.05–0.42)
TC	0.003	0.50 (0.66–0.87)	0.390	0.58 (0.85–1.24)
TBIL	0.035	1.00 (1.05–1.09)	0.426	0.97 (1.02–1.07)
NLR		1.33 (1.62–1.99)	0.280	0.89 (1.16–1.53)
CK-MB		1.38 (1.85–2.48)	0.915	0.65 (1.03–1.63)
cTnI		5.23 (11.93–27.21)	0.001	1.92 (5.05–13.31)
MYO		1.02 (1.04–1.06)	0.895	0.97 (1.00–1.02)
BNP – B-type natriuretic peptide; UA – uric acid; Apo-A1 – apolipoprotein-A1; TC – total cholesterol; TBIL – total bilirubin; NLR – neutrophil-lymphocyte ratio; CK-MB – creatine kinase-MB; cTnI – cardiac troponin I; MYO – myoglobin.