Clinical Course of 53 Previously Vaccinated Patients Admitted to the National Hospital in Warsaw, Poland with COVID-19 Between November 2021 and March 2022

Artur Zaczyński; Michał Hampel; Paweł Piątkiewicz; Jacek Nasiłowski; Sławomir Butkiewicz; Urszula Religioni; Agnieszka Barańska; Maria Malm; Agnieszka Neumann-Podczaska; Regis Vaillancourt; Piotr Merks

doi:10.12659/MSM.939841

29 April 2023 : Database Analysis

Clinical Course of 53 Previously Vaccinated Patients Admitted to the National Hospital in Warsaw, Poland with COVID-19 Between November 2021 and March 2022

Artur Zaczyński^1AB, Michał Hampel^1AB, Paweł Piątkiewicz^2AB*, Jacek Nasiłowski^3AB, Sławomir Butkiewicz^2AB, Urszula Religioni^4DEF, Agnieszka Barańska^5CD, Maria Malm

^5CD, Agnieszka Neumann-Podczaska

^6DEF, Regis Vaillancourt^2ACDF, Piotr Merks^2AFG

DOI: 10.12659/MSM.939841

Med Sci Monit 2023; 29:e939841

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Table 3 Severity of COVID-19 vs type of vaccine.

Characteristic	N	Vaccine					P value1
Characteristic	N	Overall, N=53	Astra, N=17	Johnson, N=9	Moderna, N=4	Pfizer, N=23	P value1
	52						0.915
Median [IQR]		11.5 [7.8, 16.2]	12.0 [7.0, 20.0]	10.0 [8.0, 17.0]	10.0 [6.0, 14.2]	12.0 \|[9.0, 14.0]
Range		1, 33	1, 33	5, 25	3, 18	4, 32
	53						0.516
Yes		10 (18.9%)	5 (29.4%)	2 (22.2%)	0 (0.0%)	3 (13.0%)
No		43 (81.1%)	12 (70.6%)	7 (77.8%)	4 (100.0%)	20 (87.0%)
	10						0.224
Median [IQR]		9.0 [6.2, 10.0]	6.0 [4.0, 10.0]	7.5 [7.2, 7.8]	NA [NA, NA]	10.0 [10.0, 12.5]
Range		2, 15	2, 13	7, 8	NA, NA	10, 15
	53						0.244
Mean (SD)		31.3 (21.5)	33.2 (20.8)	28.9 (12.9)	11.2 (8.5)	34.3 (24.9)
Range		0, 80	10, 80	10, 50	0, 20	0, 80
	53						0.951
Lack		14 (26.4%)	5 (29.4%)	1 (11.1%)	1 (25.0%)	7 (30.4%)
Nasal canula		18 (34.0%)	7 (41.2%)	4 (44.4%)	2 (50.0%)	5 (21.7%)
Simple oxygen mask		5 (9.4%)	1 (5.9%)	1 (11.1%)	0 (0.0%)	3 (13.0%)
Non-rebreather mask		15 (28.3%)	4 (23.5%)	3 (33.3%)	1 (25.0%)	7 (30.4%)
High-flow oxygen therapy		0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)
NIV		1 (1.9%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	1 (4.3%)
Respirator therapy		0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)	0 (0.0%)
	53						0.904
Lack		7 (13.2%)	3 (17.6%)	0 (0.0%)	1 (25.0%)	3 (13.0%)
Nasal canula		11 (20.8%)	2 (11.8%)	2 (22.2%)	1 (25.0%)	6 (26.1%)
Simple oxygen mask		7 (13.2%)	2 (11.8%)	2 (22.2%)	0 (0.0%)	3 (13.0%)
Non-rebreather mask		13 (24.5%)	3 (17.6%)	1 (11.1%)	2 (50.0%)	7 (30.4%)
High-flow oxygen therapy		4 (7.5%)	2 (11.8%)	1 (11.1%)	0 (0.0%)	1 (4.3%)
NIV		5 (9.4%)	2 (11.8%)	1 (11.1%)	0 (0.0%)	2 (8.7%)
Respirator therapy		6 (11.3%)	3 (17.6%)	2 (22.2%)	0 (0.0%)	1 (4.3%)
	53						0.289
No change		16 (30.2%)	3 (17.6%)	2 (22.2%)	2 (50.0%)	9 (39.1%)
Worsening		33 (62.3%)	14 (82.4%)	6 (66.7%)	2 (50.0%)	11 (47.8%)
Improvement		4 (7.5%)	0 (0.0%)	1 (11.1%)	0 (0.0%)	3 (13.0%)
	53						0.660
Yes		9 (17.0%)	4 (23.5%)	2 (22.2%)	0 (0.0%)	3 (13.0%)
No		44 (83.0%)	13 (76.5%)	7 (77.8%)	4 (100.0%)	20 (87.0%)
¹ Kruskal-Wallis rank sum test; Fisher’s exact test; One-way ANOVA. IQR – interquartile range; ICU – Intensive Care Unit; CT – computed tomography; NIV – non-invasive ventilation.

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Clinical Course of 53 Previously Vaccinated Patients Admitted to the National Hospital in Warsaw, Poland with COVID-19 Between November 2021 and March 2022

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