29 April 2023>: Database Analysis
Clinical Course of 53 Previously Vaccinated Patients Admitted to the National Hospital in Warsaw, Poland with COVID-19 Between November 2021 and March 2022
Artur Zaczyński 1AB , Michał Hampel 1AB , Paweł Piątkiewicz 2AB* , Jacek Nasiłowski 3AB , Sławomir Butkiewicz 2AB , Urszula Religioni 4DEF , Agnieszka Barańska 5CD , Maria Malm 5CD , Agnieszka Neuman-Podczaska 6DEF , Regis Vaillancourt 2ACDF , Piotr Merks 2AFGDOI: 10.12659/MSM.939841
Med Sci Monit 2023; 29:e939841
Table 5 Severity of the course of COVID-19 vs age.
Characteristic | N | Age [years] | P value1 | ||||
---|---|---|---|---|---|---|---|
Overall, N=52 | [40,59], N=13 | [59,65], N=15 | [65,69], N=12 | [69,90], N=12 | |||
51 | 0.659 | ||||||
Mean (SD) | 12.9 (7.1) | 11.4 (6.8) | 14.8 (7.7) | 12.4 (5.8) | 12.7 (8.1) | ||
Range | 1, 33 | 3, 25 | 5, 33 | 1, 20 | 3, 32 | ||
52 | 0.964 | ||||||
Yes | 10 (19.2%) | 2 (15.4%) | 3 (20.0%) | 3 (25.0%) | 2 (16.7%) | ||
No | 42 (80.8%) | 11 (84.6%) | 12 (80.0%) | 9 (75.0%) | 10 (83.3%) | ||
10 | 0.087 | ||||||
Median [IQR] | 9.0 [6.2, 10.0] | 11.5 [9.8, 13.2] | 10.0 [10.0, 11.5] | 4.0 [3.0, 5.0] | 8.5 [7.8, 9.2] | ||
Range | 2, 15 | 8, 15 | 10, 13 | 2, 6 | 7, 10 | ||
52 | 0.330 | ||||||
Median [IQR] | 30.0 [15.0, 50.0] | 25.0 [15.0, 40.0] | 40.0 [17.5, 50.0] | 30.0 [20.0, 50.0] | 20.0 [5.0, 36.2] | ||
Range | 0, 80 | 0, 70 | 10, 80 | 0, 80 | 5, 60 | ||
52 | 0.346 | ||||||
Lack | 13 (25.0%) | 6 (46.2%) | 3 (20.0%) | 1 (8.3%) | 3 (25.0%) | ||
Nasal canula | 18 (34.6%) | 4 (30.8%) | 5 (33.3%) | 6 (50.0%) | 3 (25.0%) | ||
Simple oxygen mask | 5 (9.6%) | 2 (15.4%) | 2 (13.3%) | 0 (0.0%) | 1 (8.3%) | ||
Non-rebreather mask | 15 (28.8%) | 1 (7.7%) | 4 (26.7%) | 5 (41.7%) | 5 (41.7%) | ||
High-flow oxygen therapy | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | ||
NIV | 1 (1.9%) | 0 (0.0%) | 1 (6.7%) | 0 (0.0%) | 0 (0.0%) | ||
Respirator therapy | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | ||
52 | 0.804 | ||||||
Lack | 7 (13.5%) | 3 (23.1%) | 1 (6.7%) | 1 (8.3%) | 2 (16.7%) | ||
Nasal canula | 10 (19.2%) | 2 (15.4%) | 4 (26.7%) | 1 (8.3%) | 3 (25.0%) | ||
Simple oxygen mask | 7 (13.5%) | 3 (23.1%) | 1 (6.7%) | 2 (16.7%) | 1 (8.3%) | ||
Non-rebreather mask | 13 (25.0%) | 1 (7.7%) | 3 (20.0%) | 4 (33.3%) | 5 (41.7%) | ||
High-flow oxygen therapy | 4 (7.7%) | 1 (7.7%) | 2 (13.3%) | 1 (8.3%) | 0 (0.0%) | ||
NIV | 5 (9.6%) | 1 (7.7%) | 3 (20.0%) | 1 (8.3%) | 0 (0.0%) | ||
Respirator therapy | 6 (11.5%) | 2 (15.4%) | 1 (6.7%) | 2 (16.7%) | 1 (8.3%) | ||
52 | 0.167 | ||||||
No change | 16 (30.8%) | 4 (30.8%) | 2 (13.3%) | 3 (25.0%) | 7 (58.3%) | ||
Worsening | 32 (61.5%) | 8 (61.5%) | 11 (73.3%) | 9 (75.0%) | 4 (33.3%) | ||
Improvement | 4 (7.7%) | 1 (7.7%) | 2 (13.3%) | 0 (0.0%) | 1 (8.3%) | ||
52 | 0.922 | ||||||
Yes | 9 (17.3%) | 2 (15.4%) | 2 (13.3%) | 3 (25.0%) | 2 (16.7%) | ||
No | 43 (82.7%) | 11 (84.6%) | 13 (86.7%) | 9 (75.0%) | 10 (83.3%) | ||
1 One-way ANOVA; Fisher’s exact test; Kruskal-Wallis rank sum test. IQR – interquartile range; ICU – Intensive Care Unit; CT – computed tomography’; NIV – non-invasive ventilation. |