Risk Factors for New Vertebral Compression Fracture After Percutaneous Vertebral Augmentation: A Retrospective Study

18 July 2023: Clinical Research

Yunfeng Zhang ^ABCE , Jiayang J. Sun ^BCD , Zhuo Zhang ^BCD , Fei Huang ^CDF , Jiayin Lv ^CDF , Qingsan Zhu ^AG*

DOI: 10.12659/MSM.940134

Med Sci Monit 2023; 29:e940134

Table 1 Univariable analysis of the Control group and NVCF group.

Variable	Overall (n=279)	Control group (n=232)	NVCF group (n=47)	P
Age (years)	71.11±8.84	70.60±8.59	73.64±9.70	0.033^*
Gender (n, %)				0.866
Female	228 (81.7)	190 (81.9)	38 (80.9)
Male	51 (18.3)	42 (18.1)	9 (19.1)
BMI (kg/m)	22.77±3.17	23.04±3.16	21.43±2.92	0.002^*
Hypertension (n, %)				0.115
No	167 (59.9)	134 (57.8)	33 (70.2)
Yes	112 (40.1)	98 (42.2)	14 (29.8)
Diabetes (n, %)				0.511
No	228 (81.7)	188 (81.0)	40 (85.1)
Yes	51 (18.3)	44 (19.0)	7 (14.9)
History of smoking (n, %)				0.270
No	245 (87.8)	206 (88.8)	39 (83.0)
Yes	34 (12.2)	26 (11.2)	8 (17.0)
History of alcohol (n, %)				0.745
No	258 (92.5)	214 (92.2)	44 (93.6)
Yes	21 (7.5)	18 (7.8)	3 (6.4)
Fracture level (n, %)				0.090
Non-TL junction	73 (26.2)	56 (24.1)	17 (36.2)
TL junction	206 (73.8)	176 (75.9)	30 (63.8)
Surgical method (n, %)				0.853
PVP	199 (71.3)	166 (71.6)	33 (70.2)
PKP	80 (28.7)	66 (28.4)	14 (29.8)
Bone cement leakage (n, %)				0.733
No	190 (68.1)	157 (67.7)	33 (70.2)
Yes	89 (31.9)	75 (32.3)	14 (29.8)
Bone cement volume (ml)	4.51±0.81	4.50±0.82	4.55±0.75	0.699
HU value	72.23±26.98	77.69±24.63	45.27±21.45	0.000^*
AVHR	0.72±0.13	0.71±0.13	0.75±0.14	0.070
NVCF – new vertebral compression fracture; BMI – body mass index; TL – thoracolumbar; PVP – percutaneous vertebroplasty; PKP – percutaneous kyphoplasty; HU – Hounsfield unit; AVHR – anterior vertebral height ratio. ^* P